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Synthesis and Evaluation of diaryl ether modulators of the leukotriene A4 hydrolase aminopeptidase activity

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116459Source: DataRank Database

Synthesis and Evaluation of diaryl ether modulators of the leukotriene A4 hydrolase aminopeptidase activity is a research paper published in European Journal of Medicinal Chemistry (2024). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 0.35)OA: greenTopics (45)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Kyung Hyeon Lee ORCID,Michael Girgis,Zachary Shellnutt ORCID,Zach Beaulac,Jiangdong Xiang ORCID

Live enrichment

PubMed:38704942 OpenAlex:https://openalex.org/W4396621356

National Cancer Institute

Grant: ACB-12002

Argonne National Laboratory

Grant: DE-AC02-06CH11357

National Institute of General Medical Sciences

Grant: AGM-12006

National Institute of General Medical Sciences

Grant: P30GM138396

National Institutes of Health

Grant: R01HL167202

National Institutes of Health

Grant: R01HL132287

National Institutes of Health

Grant: R01HL132177

National Institutes of Health

Grant: K08HL091127

Office of Science

U.S. Department of Energy

FWCI

0.35

Citation Percentile

0.6%

Citation Trend

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://www.osti.gov/biblio/2346244

publisherhttps://api.elsevier.com/content/article/PII:S0223523424003398?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0223523424003398?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ejmech.2024.116459

Fields of Study

Peptidase Inhibition and AnalysisCarbohydrate Chemistry and SynthesisChemical Synthesis and AnalysisEpoxide HydrolasesAnimalsMiceStructure-Activity RelationshipHumansMolecular StructureAminopeptidasesEthersDose-Response Relationship, DrugModels, MolecularCrystallography, X-Ray

MeSH Terms

AminopeptidasesAnimalsDose-Response Relationship, DrugEpoxide HydrolasesEthersHumansModels, MolecularStructure-Activity RelationshipMolecular StructureCrystallography, X-RayMice

Keywords

ChemistryHydrolaseEtherAminopeptidaseLeukotriene C4Leukotriene B4EnzymeStereochemistryEnzyme inhibitorChemical synthesisBiochemistryLeukotrieneIn vitroOrganic chemistryAmino acidLeucineInternal medicineEnzyme activationLeukotriene A(4)hydrolaseUllmann Cross-coupling

Sustainable Development Goals

SDG 0: Clean water and sanitation