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Antimicrobial cetylpyridinium chloride causes functional inhibition of mitochondria as potently as canonical mitotoxicants, nanostructural disruption of mitochondria, and mitochondrial Ca2+ efflux in living rodent and primary human cells

Food and Chemical Toxicology(2024)10.1016/j.fct.2024.114547Source: DataRank Database

Antimicrobial cetylpyridinium chloride causes functional inhibition of mitochondria as potently as canonical mitotoxicants, nanostructural disruption of mitochondria, and mitochondrial Ca2+ efflux in living rodent and primary human cells is a research paper published in Food and Chemical Toxicology (2024). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 1.70)OA: greenTopics (46)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

John E. Burnell,Brandon M. Aho ORCID,Bright Obeng,Emily L. Ledue,Juyoung K. Shim

Live enrichment

PubMed:38408634 PMC:PMC11060648 OpenAlex:https://openalex.org/W4392128319

NIGMS NIH HHS

Grant: R15 GM139070

NIGMS NIH HHS

Grant: P20 GM103423

University of Maine

National Institute of General Medical Sciences

FWCI

1.70

Citation Percentile

0.8%

Citation Trend

2024

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11060648/pdf/nihms-1974519.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0278691524001133?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0278691524001133?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11060648

Fields of Study

Neuroscience and Neuropharmacology ResearchDrug Transport and Resistance MechanismsLipid Membrane Structure and BehaviorMiceHumansRatsAnimalsCetylpyridiniumRodentiaAnti-Infective AgentsMitochondriaAdenosine TriphosphateAnti-Infective Agents, Local

MeSH Terms

Adenosine TriphosphateAnimalsAnti-Infective AgentsAnti-Infective Agents, LocalCetylpyridiniumHumansMitochondriaRodentiaMiceRats

Keywords

MitochondrionATP synthaseCetylpyridinium chlorideCell biologyEffluxProgrammed cell deathChemistryCell cultureBiologyBiochemistryApoptosisEnzymeMitochondriaATPMast cellKeratinocyteOxygen consumption rateAntibacterial AgentSuper-resolution MicroscopyMitochondrial CalciumQuaternary Ammonium CompoundMitotoxicityFluorescence Photoactivation Localization Microscopy (Fpalm)