From elements to modules: regulatory evolution in Ascomycota fungi is a research paper published in Current Opinion in Genetics & Development (2009). On theSindex it has a DataRank of 0.909. It has been cited 47 times, with 9 citing works in its 1-hop citation network.
Regulatory divergence is likely a major driving force in evolution. Comparative transcriptomics provides a new glimpse into the evolution of gene regulation. Ascomycota fungi are uniquely suited among eukaryotes for studies of regulatory evolution, because of broad phylogenetic scope, many sequenced genomes, and facility of genomic analysis. Here we review the substantial divergence in gene expression in Ascomycota and how this is reconciled with the modular organization of transcriptional networks. We show that flexibility and redundancy in both cis-regulation and trans-regulation can lead to changes from altered expression of single genes to wholesale rewiring of regulatory modules. Redundancy thus emerges as a major driving force facilitating expression divergence while preserving the coherent functional organization of a transcriptional response.
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Base Score Contribution
0.581
From this paper's citation signal
Citation Network Contribution
0.328
From 9 citing papers with measurable signal
Ranked by citation count — the same ordering the engine uses when summing log1p(Cq) over citers.
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 64% comes from its base citations and 36% from the citation network (9 citing papers contributed measurable signal).
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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