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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

Immunity(2020)10.1016/j.immuni.2020.03.004Source: DataRank Database

The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling is a research paper published in Immunity (2020). On theSindex it has a DataRank of 0. It has been cited 221 times.

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Open Access221 citations

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Enrichment:Funding (11 grants)OA: greenTopics (33)IDs (PubMed, PMC)Annotations (2)

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Open Access

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Reusable (0/3)

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Authors (24)

Rosa A. Sierra,Jimena Trillo-Tinoco ORCID,Yu Cao ORCID,Patrick Innamarato ORCID,Kyle K. Payne ORCID

Live enrichment

PubMed:32294407 PMC:PMC7207019

NCI NIH HHS

Grant: P30 CA076292

NCI NIH HHS

Grant: R01 CA103320

NCI NIH HHS

Grant: R01 CA184185

NCI NIH HHS

Grant: R01 CA211229

NCI NIH HHS

Grant: R01 CA157664

NCI NIH HHS

Grant: R01 CA233512

NCI NIH HHS

Grant: R01 CA124515

NCI NIH HHS

Grant: T32 CA009140

NCI NIH HHS

Grant: R01 CA178687

National Institutes of Health

Ovarian Cancer Academy

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7207019

publisherhttps://api.elsevier.com/content/article/PII:S1074761320301175?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1074761320301175?httpAccept=text/plain

MeSH Terms

CD8-Positive T-LymphocytesMitochondriaAnimalsMice, Inbred C57BLMice, KnockoutHumansMiceMelanoma, ExperimentalCarcinoma, Lewis LungSkin NeoplasmseIF-2 KinaseInterferon-alphaInterferon-betaMembrane ProteinsReceptors, InterferonSignal TransductionGene Expression Regulation, NeoplasticFemaleMaleNF-E2-Related Factor 2Unfolded Protein ResponseMyeloid-Derived Suppressor CellsCarcinoma, Ovarian EpithelialImmunosuppression TherapySTING Protein

Keywords

tumor immunityER stressNRF2pERKType I IfnMdscsStingUnfolded Protein Responses

The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

FAIR Checklist

Authors (24)

Funding (11 grants)

Open Access

Topics

Annotations (Europe PMC)