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Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment

Immunity(2020)10.1016/j.immuni.2020.08.005Source: DataRank Database

Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment is a research paper published in Immunity (2020). On theSindex it has a DataRank of 0. It has been cited 230 times.

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Open Access230 citations

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Enrichment:Funding (10 grants)OA: hybridTopics (60)IDs (PubMed, PMC)Annotations (4)SDGs (1)

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Open Access

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Authors (20)

Asaf Madi ORCID,Huiyuan Zhang ORCID,Max Klapholz ORCID,Giulia Escobar ORCID,Shai Dulberg ORCID

Live enrichment

PubMed:32937153 PMC:PMC7682805

Swiss National Science Foundation

Grant: 183910

Dissecting the role of Wnt signaling in the regulation of IL-17-producing cells during inflammatory bowel disease and cancer

NIAID NIH HHS

Grant: P01 AI073748

NCI NIH HHS

Grant: R01 CA229400

NINDS NIH HHS

Grant: R01 NS045937

NCI NIH HHS

Grant: P01 CA128814

NIAID NIH HHS

Grant: P01 AI056299

National Institutes of Health

Grant: 5R01CA229400-04

Steroid hormone regulation of immune responses

National Institutes of Health

Grant: 5R01NS045937-07

Role of Th1 specific cell surface molecule Tim-3 in EAE.

National Institutes of Health

Grant: 5P01AI073748-02

Transgenic/Knock-out Mouse

National Institutes of Health

hybridLicense: Elsevier Non-Commercial

publisherhttps://api.elsevier.com/content/article/PII:S1074761320303587?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1074761320303587?httpAccept=text/plain

https://doi.org/10.1016/j.immuni.2020.08.005

http://www.cell.com/article/S1074761320303587/pdf

https://pubmed.ncbi.nlm.nih.gov/32937153

Fields of Study

03 medical and health sciences0302 clinical medicineAnimalsCD8-Positive T-LymphocytesCell Line, TumorGlucocorticoidsHematopoiesisHepatocyte Nuclear Factor 1-alphaImmune Checkpoint InhibitorsLymphocyte ActivationMacrophagesMelanoma, ExperimentalMiceMice, Inbred C57BLMice, KnockoutReceptors, GlucocorticoidSignal TransductionTumor Microenvironment

MeSH Terms

CD8-Positive T-LymphocytesCell Line, TumorMacrophagesAnimalsMice, Inbred C57BLMice, KnockoutMiceMelanoma, ExperimentalReceptors, GlucocorticoidGlucocorticoidsLymphocyte ActivationSignal TransductionHematopoiesisHepatocyte Nuclear Factor 1-alphaTumor MicroenvironmentImmune Checkpoint Inhibitors

Keywords

CancerSteroidGlucocorticoidDysfunctionExhaustionTumor-associated MacrophagesNr3c1Immune Checkpoint BlockadeTcf-1Cd8(+) T cellMice, KnockoutMacrophagesMelanoma, ExperimentalCD8-Positive T-LymphocytesLymphocyte ActivationHematopoiesisMice, Inbred C57BLMiceReceptors, GlucocorticoidCell Line, TumorTumor MicroenvironmentAnimalsHepatocyte Nuclear Factor 1-alphaGlucocorticoidsImmune Checkpoint InhibitorsSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health

Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment

FAIR Checklist

Authors (20)

Funding (10 grants)

Open Access

Topics

Annotations (Europe PMC)