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Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer’s disease

Immunity(2023)10.1016/j.immuni.2023.08.008Source: DataRank Database

Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer’s disease is a research paper published in Immunity (2023). On theSindex it has a DataRank of 0. It has been cited 72 times.

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Open Access72 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 6.70)OA: hybridTopics (40)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (25)

Chuanpeng Dong ORCID,Peter Bor‐Chian Lin ORCID,Adrian L. Oblak ORCID,Gonzalo Viana Di Prisco ORCID,Nian Wang ORCID

Live enrichment

PubMed:37659412 PMC:PMC10564391 OpenAlex:https://openalex.org/W4386369314

National Institute on Aging

Grant: U54 AG054345

National Institute on Aging

Grant: K01 AG054753

National Institute on Aging

Grant: RF1 AG074566

National Institute of Neurological Disorders and Stroke

Grant: R03 AG063250

National Institute of Neurological Disorders and Stroke

Grant: R01 NS125020

NLM

Grant: NLM R01 LM012535

NLM NIH HHS

Grant: R01 LM012535

NIA NIH HHS

Grant: R01 AG074566

NIGMS NIH HHS

Grant: R35 GM149299

National Institutes of Health

FWCI

6.70

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S1074761323003643/pdf

publisherhttp://www.cell.com/article/S1074761323003643/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1074761323003643?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1074761323003643?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.immuni.2023.08.008

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsNuclear Receptors and Signaling

MeSH Terms

Alzheimer DiseaseAnimalsPhagocytosisPhenotypeMicrogliaMicePhospholipase C gammaGenetic Association StudiesPlaque, Amyloid

Keywords

MicrogliaBiologyPhenotypeDiseaseAlzheimer's diseaseFunction (biology)GeneticsNeurosciencePhospholipaseGeneDifferential (mechanical device)TREM2Computational biologyImmunologyMedicineInflammationPathologyEnzymeBiochemistryAlzheimer’s diseaseneuroinflammationSynaptic FunctionAmyloid PathologyTranscriptional ProgramsP522r And M28l VariantMicroglia-plaque InteractionsMicroglial Uptake CapacityPhospholipase C-gamma-2

Sustainable Development Goals

SDG 0: Good health and well-being

Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer’s disease

FAIR Checklist

Authors (25)

Funding (10 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)