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Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis

Immunity(2024)10.1016/j.immuni.2024.11.006Source: DataRank Database

Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis is a research paper published in Immunity (2024). On theSindex it has a DataRank of 0. It has been cited 29 times.

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Open Access29 citations

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Enrichment:Funding (7 grants)Impact (FWCI 4.56)OA: greenTopics (45)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (19)

Maria Mesina,Jinyong Choi ORCID,Simon Bélanger ORCID,Monique Marshall,Christopher M. Tipton ORCID

Live enrichment

PubMed:39612915 PMC:PMC11675998 OpenAlex:https://openalex.org/W4404817511

National Institutes of Health

Grant: P01 AI145815

National Institutes of Health

Grant: CHAVD-ID UM1AI100663

National Institutes of Health

Grant: CHAVD UM1AI144462

NIAID NIH HHS

Grant: UM1 AI144462

NIAID NIH HHS

Grant: UM1 AI100663

NIAID NIH HHS

Grant: P01 AI125180

NIAID NIH HHS

Grant: P01 AI078907

FWCI

4.56

Citation Percentile

1.0%

Citation Trend

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11675998/pdf/nihms-2035256.pdf

publisherhttps://api.elsevier.com/content/article/PII:S1074761324005211?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1074761324005211?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11675998/

Fields of Study

Immune Cell Function and InteractionT-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

MeSH Terms

Positive Regulatory Domain I-Binding Factor 1Interferon Regulatory Factor-4AnimalsB-LymphocytesCell DifferentiationT-Lymphocytes, Helper-InducerImmunoglobulin GInterleukin-2Lymphocyte ActivationMice, Inbred C57BLPlasma CellsSignal TransductionMice, KnockoutGerminal CenterInterferon Regulatory FactorsProto-Oncogene Proteins c-aktMiceInterleukin-2 Receptor alpha SubunitTOR Serine-Threonine Kinases

Keywords

BiologyPI3K/AKT/mTOR pathwayB cellCell biologyProtein kinase BFollicular phaseCellInterleukin 4ImmunologyCancer researchSignal transductionCytokineEndocrinologyGeneticsAntibodiesMetabolismVaccinePlasma cellsMtorT Follicular Helper CellsTfh CellsIl-2 CytokineCd4 T cells

Sustainable Development Goals

SDG 0: Zero hunger

Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis

FAIR Checklist

Authors (19)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)