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Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity

Immunity(2025)10.1016/j.immuni.2025.04.020Source: DataRank Database

Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity is a research paper published in Immunity (2025). On theSindex it has a DataRank of 0. It has been cited 18 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access18 citations

Cite:

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (33 grants)Impact (FWCI 6.89)OA: greenTopics (53)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (32)

Benxia Hu,Yalan Deng ORCID,Melinda Soeung ORCID,Jun Yao ORCID,Lanxin Bei ORCID

Live enrichment

PubMed:40359940 PMC:PMC12186235 OpenAlex:https://openalex.org/W4410314244

National Institutes of Health

Grant: R01CA255080

National Institutes of Health National Cancer Institute

Grant: R01CA218025

National Institutes of Health National Cancer Institute

Grant: R01CA231011

National Institutes of Health National Cancer Institute

Grant: R01CA285454

National Institutes of Health National Cancer Institute

Grant: R01CA218036

National Institutes of Health National Cancer Institute

Grant: R01CA269489

American Association for Cancer Research

Grant: 20-60-51

U.S. Department of Defense

Grant: KC220138

U.S. Department of Defense

Grant: RA230062

U.S. Department of Defense

Grant: BC230333

U.S. Department of Defense

Grant: KC200096P1

U.S. Department of Defense

Grant: MD200001

U.S. Department of Defense

Grant: R01HD110520

Welch Foundation

Grant: AU-2000-20220331

Cancer Prevention and Research Institute of Texas

Grant: RP200423

Cancer Prevention and Research Institute of Texas

Grant: RP180259

Cancer Prevention and Research Institute of Texas

Grant: RP210045

NCI NIH HHS

Grant: R01 CA269646

NCI NIH HHS

Grant: R01 CA282282

NIGMS NIH HHS

Grant: R01 GM136922

NCI NIH HHS

Grant: R37 CA288448

NCI NIH HHS

Grant: P30 CA016672

NCI NIH HHS

Grant: R01 CA247992

NHLBI NIH HHS

Grant: U01 HL156059

NCI NIH HHS

Grant: U54 CA274220

NCI NIH HHS

Grant: R01 CA244144

NIA NIH HHS

Grant: R01 AG082132

V Foundation for Cancer Research

Gateway for Cancer Research

Johnson Foundation

Kidney Cancer Association

Prometheus

National Institute on Aging

FWCI

6.89

Citation Percentile

1.0%

Citation Trend

2025

2026

greenLicense: http://creativecommons.org/licenses/by-nc-nd/4.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12186235/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12186235/

publisherhttps://api.elsevier.com/content/article/PII:S1074761325001839?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1074761325001839?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.immuni.2025.04.020

Fields of Study

Epigenetics and DNA MethylationRNA modifications and cancerFerroptosis and cancer prognosisFerroptosisAnimalsCD8-Positive T-LymphocytesMiceAnemia, Sickle CellHumansChromatinTumor MicroenvironmentAmino Acid Transport System y+NeoplasmsDisease Models, AnimalMice, Inbred C57BL

MeSH Terms

FerroptosisAnemia, Sickle CellAnimalsChromatinDisease Models, AnimalHumansMice, Inbred C57BLNeoplasmsCD8-Positive T-LymphocytesAmino Acid Transport System y+MiceTumor Microenvironment

Keywords

BiologyImmunityChromatinDiseaseCD8ImmunologyCytotoxic T cellCell mediated immunityCellCancer researchCell biologyImmune systemGeneticsInternal medicineMedicineDNASickle Cell DiseaseRenal Medullary CarcinomaHi-cSmarcb1Cd8(+) T CellsFerroptosisH(2)sImmune Checkpoint InhibitorsSlc7a11Genomic Architecture Alteration