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Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity

Immunity(2025)10.1016/j.immuni.2025.09.014Source: DataRank Database

Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity is a research paper published in Immunity (2025). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (20 grants)Impact (FWCI 2.84)OA: hybridTopics (61)IDs (PubMed, OpenAlex)

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Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (23)

Randy Yoo ORCID,Sophia Hailemariam ORCID,Fabian Heide ORCID,Danton Ivanochko ORCID,Matthew R. Jackman ORCID

Live enrichment

PubMed:41072404 OpenAlex:https://openalex.org/W4415012406

National Institutes of Health

Grant: R01-GM129325

Japan Agency for Medical Research and Development

Grant: JP24wm0225045

Federation of European Microbiological Societies

Grant: VI.Veni.222.381

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Grant: 192.061

Canadian Institutes of Health Research

Grant: 428410

Brookhaven National Laboratory

Grant: DE-SC0012704

Natural Sciences and Engineering Research Council of Canada

Grant: unidentified

unidentified

Office of Science

University of Saskatchewan

Canada Foundation for Innovation

National Research Council

Canada Research Chairs

National Institute of Allergy and Infectious Diseases

KWF Kankerbestrijding

Oncode Institute

U.S. Department of Energy

Government of Saskatchewan

Hospital for Sick Children

National Research Council Canada

Natural Sciences and Engineering Research Council of Canada

FWCI

2.84

Citation Percentile

0.9%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1016/j.immuni.2025.09.014

publisherhttps://doi.org/10.1016/j.immuni.2025.09.014

publisherhttps://api.elsevier.com/content/article/PII:S107476132500425X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S107476132500425X?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41072404

Fields of Study

RNA and protein synthesis mechanismsCRISPR and Genetic EngineeringMalaria Research and Control0303 health sciences03 medical and health sciencesCryoelectron MicroscopyPlasmodium falciparumProtozoan ProteinsAnimalsAntibodies, ProtozoanMalaria, FalciparumAntigens, ProtozoanHumansMalaria VaccinesEpitopesAntibodies, BlockingProtein BindingMembrane Glycoproteins

MeSH Terms

AnimalsAntibodies, ProtozoanEpitopesAntigens, ProtozoanHumansMembrane GlycoproteinsPlasmodium falciparumProtein BindingProtozoan ProteinsMalaria, FalciparumMalaria VaccinesAntibodies, BlockingCryoelectron Microscopy

Keywords

Plasmodium falciparumEpitopeAntibodyMalariaEndogenyProtein structurePeptide sequenceImmune systemMonoclonal antibodiesCryo-electron microscopyPfs48/45TbvPfs230Transmission-reducing ActivityTransmission-blocking VaccinesTransmission-blocking AntibodiesMedical Microbiology - Radboud University Medical CenterMembrane GlycoproteinsCryoelectron MicroscopyProtozoan ProteinsAntibodies, ProtozoanAntigens, ProtozoanEpitopesMalaria VaccinesAnimalsHumansMalaria, FalciparumAntibodies, BlockingMolecular BiologyProtein Binding