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HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2

International Immunopharmacology(2020)10.1016/j.intimp.2020.106383Source: DataRank Database

HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2 is a research paper published in International Immunopharmacology (2020). On theSindex it has a DataRank of 0. It has been cited 26 times.

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26 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 3.15)OA: closedTopics (69)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Jing Ji ORCID,Chunxiao Liu ORCID,Mengze Zhou ORCID,Huanqiu Li ORCID,Shumin Ye

Live enrichment

PubMed:32193099 OpenAlex:https://openalex.org/W3012275118

National Institutes of Health

Grant: 80-23

National Natural Science Foundation of China

Grant: CPU2018GF02

National Natural Science Foundation of China

Grant: NSFC81773745

FWCI

3.15

Citation Percentile

0.9%

Influential Citations

Citation Trend

2020

2021

2022

2023

2024

2025

2026

closedLicense: https://www.elsevier.com/legal/tdmrep-license

publisherhttps://api.elsevier.com/content/article/PII:S1567576919327948?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1567576919327948?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.intimp.2020.106383

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32193099

Fields of Study

Piperaceae Chemical and Biological StudiesMedicinal Plants and NeuroprotectionOlfactory and Sensory Function StudiesMedicineChemistryAnimalsHumansRatsAlkaloidsApoptosisBenzodioxolesCells, CulturedCognitive DysfunctionDisease Models, AnimalIbotenic AcidInflammasomesInflammationKelch-Like ECH-Associated Protein 1NeuronsOxidative StressPiperidinesPolyunsaturated AlkamidesProtein BindingProtein Interaction Domains and MotifsRats, Sprague-DawleyNF-E2-Related Factor 2GA-Binding Protein Transcription Factor

MeSH Terms

Kelch-Like ECH-Associated Protein 1AlkaloidsAnimalsCells, CulturedDisease Models, AnimalHumansIbotenic AcidInflammationNeuronsPiperidinesProtein BindingRats, Sprague-DawleyApoptosisOxidative StressNF-E2-Related Factor 2GA-Binding Protein Transcription FactorRatsBenzodioxolesPolyunsaturated AlkamidesProtein Interaction Domains and MotifsInflammasomesCognitive Dysfunction

Keywords

PiperineInflammationApoptosisIbotenic acidChemistryDerivative (finance)Cognitive impairmentKEAP1PharmacologyBiochemistryMedicineCognitionImmunologyBiologyNeuroscienceInternal medicineAlzheimer’s diseaseKeap1-nrf2Hj22Txnip/nlpr3 Inflammasome

Sustainable Development Goals

SDG 0: Good health and well-being