Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways

International Immunopharmacology(2021)10.1016/j.intimp.2021.107506Source: DataRank Database

Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways is a research paper published in International Immunopharmacology (2021). On theSindex it has a DataRank of 0. It has been cited 27 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

27 citations

Free full text

Cite:

Linked data & code

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 1.34)OA: closedTopics (53)Linked Datasets (6)DataCite Reuse (6)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (0/2)

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (4)

S. R. Wayne Chen ORCID,Lili Zhao ORCID,Xiaoyun Shi,Xiuhong Wang ORCID

Live enrichment

PubMed:34022766 OpenAlex:https://openalex.org/W3164755010

National Institutes of Health

Nanchang University

FWCI

1.34

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

closedLicense: https://doi.org/10.15223/policy-004

publisherhttps://api.elsevier.com/content/article/PII:S1567576921001429?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1567576921001429?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.intimp.2021.107506

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34022766

Fields of Study

Inflammasome and immune disordersImmune Response and InflammationNF-κB Signaling PathwaysAcute Lung InjuryAnimalsDisease Models, AnimalDrug Therapy, CombinationFemaleFuransHumansIndenesInflammasomesInterleukin 1 Receptor Antagonist ProteinLipopolysaccharidesMAP Kinase Signaling SystemMaleMiceNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinSulfonamides

MeSH Terms

NLR Family, Pyrin Domain-Containing 3 ProteinAnimalsDisease Models, AnimalDrug Therapy, CombinationFemaleFuransHumansIndenesLipopolysaccharidesMaleSulfonamidesNF-kappa BMAP Kinase Signaling SystemMiceInterleukin 1 Receptor Antagonist ProteinAcute Lung InjuryInflammasomes

Keywords

AnakinraInflammasomeMedicineMAPK/ERK pathwayPharmacologyNF-κBSignal transductionInflammationImmunologyInternal medicineBiologyMitogen-activated protein kinaseNuclear factor-κBAcute Lung InjuryMcc950Nucleotide Binding Domain And Leucine-rich Repeat (Nlr) Pyrin Domain Containing 3

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 2 of Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway

10.6084/m9.figshare.22621558.v1figshare

Additional file 2 of Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway

10.6084/m9.figshare.22621558figshare

Additional file 3 of Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway

10.6084/m9.figshare.22621561.v1figshare

Additional file 3 of Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway

10.6084/m9.figshare.22621561figshare

Additional file 4 of Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway

10.6084/m9.figshare.22621564.v1figshare

Additional file 4 of Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway

10.6084/m9.figshare.22621564figshare

Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways

FAIR Checklist

Authors (4)

Funding (2 grants)

Impact

Open Access

Topics

Linked Datasets (6)