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Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways

Journal of Allergy and Clinical Immunology(2020)10.1016/j.jaci.2020.07.030Source: DataRank Database

Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways is a research paper published in Journal of Allergy and Clinical Immunology (2020). On theSindex it has a DataRank of 0. It has been cited 93 times.

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Enrichment:Funding (60 grants)Impact (FWCI 5.54)OA: greenTopics (115)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (2)

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Authors (20)

Stephanie A. Christenson ORCID,Brian D. Modena ORCID,Huashi Li ORCID,William W. Busse ORCID,Mario Castro ORCID

Live enrichment

PubMed:32795586 PMC:PMC7876167 OpenAlex:https://openalex.org/W3048372645

NHLBI NIH HHS

Grant: U10 HL109257

NHLBI NIH HHS

Grant: HHSN268201500016C

NIAID NIH HHS

Grant: R01 AI149754

NCRR NIH HHS

Grant: UL1 RR024992

NCRR NIH HHS

Grant: M01 RR003186

NHLBI NIH HHS

Grant: R01 HL069130

NHLBI NIH HHS

Grant: R01 HL069167

NHLBI NIH HHS

Grant: U01 HL146002

NCATS NIH HHS

Grant: UL1 TR001863

NHLBI NIH HHS

Grant: RC2 HL101487

NHLBI NIH HHS

Grant: U01 HL137880

NHLBI NIH HHS

Grant: U10 HL109164

NCATS NIH HHS

Grant: UL1 TR002366

NHLBI NIH HHS

Grant: HHSN268201800001C

NHLBI NIH HHS

Grant: R01 HL069170

NHLBI NIH HHS

Grant: R01 HL069174

NHLBI NIH HHS

Grant: U10 HL109168

NCRR NIH HHS

Grant: M01 RR018390

NHLBI NIH HHS

Grant: P01 HL107202

NHLBI NIH HHS

Grant: R01 HL120393

NHLBI NIH HHS

Grant: U10 HL109086

NHLBI NIH HHS

Grant: U10 HL109146

NHLBI NIH HHS

Grant: U10 HL109152

NHLBI NIH HHS

Grant: U10 HL109172

NHLBI NIH HHS

Grant: K23 HL144418

NCRR NIH HHS

Grant: M01 RR007122

NHLBI NIH HHS

Grant: R01 HL069149

NHLBI NIH HHS

Grant: R01 HL117626

NHLBI NIH HHS

Grant: U01 HL120393

NHLBI NIH HHS

Grant: U10 HL109250

NCATS NIH HHS

Grant: UL1 TR002345

NHLBI NIH HHS

Grant: K23 HL123778

NHLBI NIH HHS

Grant: K24 HL137013

NHLBI NIH HHS

Grant: R01 HL069116

NHLBI NIH HHS

Grant: R01 HL069155

NHLBI NIH HHS

Grant: R01 HL069349

NHLBI NIH HHS

Grant: R01 HL087665

NHLBI NIH HHS

Grant: R01 HL091762

National Institutes of Health

Grant: 5M01RR007122-16

L-SELENIUM-BASED CHEMOPREVENTION OF PROSTATE CANCER

National Institutes of Health

Grant: 5R01HL117626-02

Studies of Rare Genetic Variation in the Isolated Population of Sardinia

National Institutes of Health

Grant: 1R01HL087665-01

Genome Wide Association for Asthma and Lung Function

National Institutes of Health

Grant: 7M01RR018390-02

Role of Hyaluronan in IBD

National Institutes of Health

Grant: 5R01HL069155-02

INFLAMMATION &CORTICOSTEROID RESPONSES IN SEVERE ASTHMA

National Institutes of Health

Grant: 5R01HL120393-03

Rare variants and NHLBI traits in deeply phenotyped cohorts

National Institutes of Health

Grant: 3M01RR003186-08S5

GCRC-MCAP-DR MAMBY

National Institutes of Health

Grant: 4U10HL109257-06

Severe Asthma Research Program (SARP)-Washington University

National Institutes of Health

Grant: 5R01HL069149-03

Airway Remodeling in Severe Asthma

National Institutes of Health

Grant: 4U10HL109168-06

Stability of Severe Asthma Phenotypes: Impact of Exacerbations

National Institutes of Health

Grant: 1U10HL109250-01

Airway redox biochemistry as a deteriminant of asthma phenotype during adolescen*

National Institutes of Health

Grant: 5R01HL069116-07

Severe Asthma from Respiratory Infections

National Institutes of Health

Grant: 5R01HL069170-09

Redox Determinants of Severe Asthma

National Institutes of Health

Grant: 5R01HL069167-10

Genotype-Phenotype Interactions in Severe Asthma

National Institutes of Health

Grant: 3UL1RR024992-03S4

Washington University Institute of Clinical and Translational Sciences (UL1)

National Institutes of Health

Grant: 7R01HL069130-05

Mechanisms of Steroid Resistance in Severe Asthma

National Institutes of Health

Grant: 5U10HL109172-03

AMSA: ALXR/FBR Mediated Signaling in Severe Asthma

National Institutes of Health

Grant: 5U10HL109152-02

Implications and Stability of Clinical and Molecular Phenotypes of Severe Asthma

National Institutes of Health

Grant: 5U10HL109146-05

Clinical and Molecular Phenotypes of Severe Asthma

National Institutes of Health

Grant: 5R01HL069174-05

IL-13, MYOFIBROBLASTS &ELASTIC RECOIL IN SEVERE ASTHMA

National Institutes of Health

Grant: 1RC2HL101487-01

Linking Genetics, Genomics and Phenomics to Better Understand Asthma Severity

National Institutes of Health

FWCI

5.54

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7876167

publisherhttps://api.elsevier.com/content/article/PII:S009167492031112X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S009167492031112X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jaci.2020.07.030

Fields of Study

Asthma and respiratory diseasesIL-33, ST2, and ILC PathwaysGenetic Associations and Epidemiology0301 basic medicine0303 health sciences03 medical and health sciencesAdultAsthmaChromosomes, Human, Pair 17Disease ProgressionGenetic Association StudiesGenotypeHumansMiddle AgedNeoplasm ProteinsPolymorphism, Single NucleotideQuantitative Trait LociRespiratory MucosaSequence Analysis, RNASeverity of Illness IndexWhole Genome SequencingGasdermins

MeSH Terms

Whole Genome SequencingGasderminsAdultAsthmaChromosomes, Human, Pair 17GenotypeHumansMiddle AgedNeoplasm ProteinsSeverity of Illness IndexSequence Analysis, RNADisease ProgressionRespiratory MucosaPolymorphism, Single NucleotideQuantitative Trait LociGenetic Association Studies

Keywords

AsthmaSingle-nucleotide polymorphismQuantitative trait locusGeneImmunologyBiologyGeneticsMedicineGenotypeEqtlRnaseqAsthma SeverityWhole-genome SequencePgap3Asthma ExacerbationsGsdmbGsdmaAntiviral PathwaysAllergyDisease Progression (mesh)Pair 17 (mesh)Lung (rcdc)Severity of Illness IndexClinical Research (rcdc)NHLBI Severe Asthma Research Program (SARP)GasderminsAsthma (rcdc)2.1 Biological and endogenous factors32 Biomedical and Clinical Sciences (for-2020)LungNHLBI Severe Asthma Research ProgramHumans (mesh)Allergy (science-metrix)Single NucleotideMiddle AgedNeoplasm ProteinsWhole Genome Sequencing (mesh)Severity of Illness Index (mesh)RespiratoryDisease ProgressionRNA (mesh)Quantitative Trait Loci (mesh)Sequence AnalysisHumanAdultSingle Nucleotide (mesh)Quantitative Trait Loci6101107 Immunology (for)Respiratory MucosaPolymorphism, Single NucleotideChromosomesClinical ResearchMiddle Aged (mesh)Respiratory (hrcs-hc)HumansPolymorphism3204 Immunology (for-2020)Genetic Association Studies (mesh)Genetic Association StudiesBiomedical and Clinical SciencesWhole Genome SequencingGenetics (rcdc)Asthma (mesh)Genotype (mesh)Sequence Analysis, RNAInflammatory and immune systemPair 17Human Genome2.1 Biological and endogenous factors (hrcs-rac)Human Genome (rcdc)Inflammatory and immune system (hrcs-hc)Adult (mesh)RNARespiratory Mucosa (mesh)Neoplasm Proteins (mesh)Chromosomes, Human, Pair 17

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways

FAIR Checklist

Authors (20)

Funding (60 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)