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CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury

Journal of Advanced Research(2022)10.1016/j.jare.2022.03.004Source: DataRank Database

CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury is a research paper published in Journal of Advanced Research (2022). On theSindex it has a DataRank of 0. It has been cited 21 times.

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Open Access21 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (15 grants)OA: goldTopics (74)IDs (PubMed, PMC)SDGs (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (44)

Thomas Duflot ORCID,Séverine Ménoret ORCID,Hind Messaoudi,Zoubir Djerada ORCID,Déborah Groussard ORCID

Live enrichment

PubMed:36585106 PMC:PMC9811321

Agence Nationale de la Recherche

Grant: ANR-11-LABX-0029

Agence Nationale de la Recherche

Grant: ANR-16-CE17-0012

Impact of the modulation of Soluble epoxide hydrolase enzymatic Activities on Pulmonary HypertensIon and Right ventricular dysfunction in experimental and human heart failure

National Institutes of Health

Grant: P42 ES004699

National Institutes of Health

Grant: R15 DK114790

National Institutes of Health

Grant: R35 ES030443

European Regional Development Fund

Grant: HN0001343

Boston Foundation for Architecture

Grant: UMR 8251

National Institutes of Health

Grant: 5R35ES030443-04

Bioactive lipids as effectors and indicators of the deleterious effects of environmental exposure on chronic diseases

National Institutes of Health

Grant: 5P42ES004699-30

Biomarkers of Exposure to Hazardous Substances

National Institutes of Health

Grant: 1R15DK114790-01A1

n-3 derived epoxides and sEH inhibitor in brown adipogenesis

Région Normandie

Université de Paris

Labex

Centre National de la Recherche Scientifique

Institut National de la Santé et de la Recherche Médicale

goldLicense: cc-by-nc-nd

publisherhttps://ars.els-cdn.com/content/image/1-s2.0-S2090123222000650-ga1_lrg.jpg

publisherhttps://api.elsevier.com/content/article/PII:S2090123222000650?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2090123222000650?httpAccept=text/plain

repositoryhttps://hal.science/hal-03836917/document

repositoryhttps://escholarship.org/content/qt1qj4r9ns/qt1qj4r9ns.pdf?t=rxhnf2

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsRatsHeart DiseasesReperfusion InjuryInsulin ResistanceObesityHeart InjuriesEpoxide HydrolasesPhosphoric Monoester HydrolasesLysophospholipidsFemaleMaleCRISPR-Cas Systems

Keywords

ObesityThermogenesisSoluble Epoxide HydrolaseLipid PhosphataseCrispr-cas9Cardiac Ischemic InjuryMaleMedicine (General)Science (General)[SDV]Life Sciences [q-bio]CardiovascularEpoxide Hydrolases (mesh)Reperfusion Injury (mesh)Q1-390Insulin Resistance (mesh)Obesity (mesh)2.1 Biological and endogenous factorsAnimals (mesh)CRISPR-Cas Systems (mesh)32 Biomedical and Clinical Sciences (for-2020)Male (mesh)Epoxide Hydrolases600Biological SciencesRats (mesh)[SDV] Life Sciences [q-bio]Reperfusion InjuryHeart Injuries (mesh)Cardiovascular (rcdc)Original ArticleFemalePhosphoric Monoester Hydrolases (mesh)Heart Diseases610Heart Diseases (mesh)R5-920GeneticsAnimalsMetabolic and endocrineNutritionObesity (rcdc)31 Biological Sciences (for-2020)Cardiovascular (hrcs-hc)Biomedical and Clinical SciencesGenetics (rcdc)2.1 Biological and endogenous factors (hrcs-rac)Phosphoric Monoester Hydrolases3101 Biochemistry and Cell Biology (for-2020)RatsNutrition (rcdc)Metabolic and endocrine (hrcs-hc)Heart InjuriesFemale (mesh)Lysophospholipids (mesh)Biochemistry and Cell BiologyCRISPR-Cas SystemsInsulin ResistanceLysophospholipids

Sustainable Development Goals

SDG 2: 2. Zero hunger