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The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100661Source: DataRank Database

The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 20 times.

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Open Access20 citations

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Enrichment:Funding (3 grants)Impact (FWCI 3.24)OA: goldTopics (37)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Xunjun Xiao ORCID,Miriam Cnop ORCID,Khadija El Jellas ORCID,Stefan Johansson ORCID,Pål R. Njølstad ORCID

Live enrichment

PubMed:33862081 PMC:PMC8692231 OpenAlex:https://openalex.org/W3153765537

NIDDK NIH HHS

Grant: R01 DK124415

National Institutes of Health

Norges forskningsråd

FWCI

3.24

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S002192582100449X/pdf

publisherhttp://www.jbc.org/article/S002192582100449X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S002192582100449X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S002192582100449X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2021.100661

Fields of Study

Pancreatic function and diabetesEndoplasmic Reticulum Stress and DiseaseMetabolism, Diabetes, and CancerEndoplasmic Reticulum StressGlycosylationHEK293 CellsHumansLipaseMinisatellite RepeatsMutationProteostasis

MeSH Terms

ProteostasisGlycosylationHumansLipaseMutationMinisatellite RepeatsHEK293 CellsEndoplasmic Reticulum Stress

Keywords

ProteotoxicityEndoplasmic reticulumBiologyGeneGeneticsLipaseCell biologyMolecular biologyProtein aggregationBiochemistryEnzymeUnfolded protein responseendoplasmic reticulum stressprotein misfoldingO-glycosylationCelMody8Single-base Deletions

Sustainable Development Goals

SDG 0: Good health and well-being

The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity

FAIR Checklist

Authors (10)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)