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The antiviral enzyme viperin inhibits cholesterol biosynthesis

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100824Source: DataRank Database

The antiviral enzyme viperin inhibits cholesterol biosynthesis is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 22 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access22 citations

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Linked data & code

uniprot pxd pdb

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 1.39)OA: goldTopics (53)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Soumi Ghosh ORCID,Ayesha M. Patel ORCID,Keerthi Sajja,James Windak,Venkatesha Basrur ORCID

Live enrichment

PubMed:34029588 PMC:PMC8254119 OpenAlex:https://openalex.org/W3165318559

NIH

Grant: DK 046960

NIH

Grant: GM 093088

NIH

Grant: GM 094231

NIDDK NIH HHS

Grant: P30 DK020572

NIDDK NIH HHS

Grant: R01 DK046960

NIDDK NIH HHS

Grant: P30 DK089503

NIGMS NIH HHS

Grant: R01 GM093088

NIGMS NIH HHS

Grant: R01 GM094231

NIDDK NIH HHS

Grant: R37 DK046960

National Institutes of Health

Grant: 3R01GM093088-02S1

Understanding hydrogen atom transfer reactions in enzymes

FWCI

1.39

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.jbc.2021.100824

publisherhttps://doi.org/10.1016/j.jbc.2021.100824

publisherhttps://api.elsevier.com/content/article/PII:S0021925821006220?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925821006220?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34029588

Fields of Study

interferon and immune responsesCholesterol and Lipid MetabolismSystemic Lupus Erythematosus Research0301 basic medicine0303 health sciences03 medical and health sciencesAntiviral AgentsBiosynthetic PathwaysCholesterolCytidine TriphosphateHEK293 CellsHumansIntramolecular TransferasesOxidoreductases Acting on CH-CH Group DonorsProtein BindingProteinsSqualene MonooxygenaseViperin Protein

MeSH Terms

Viperin ProteinAntiviral AgentsCholesterolCytidine TriphosphateHumansProtein BindingProteinsIntramolecular TransferasesOxidoreductases Acting on CH-CH Group DonorsSqualene MonooxygenaseBiosynthetic PathwaysHEK293 Cells

Keywords

BiosynthesisEnzymeBiochemistryChemistryCholesterolBiologyViperinCholesterol RegulationSqualene MonooxygenaseRadical Sam EnzymeInteractome AnalysisLanosterol SynthaseOxidoreductases Acting on CH-CH Group DonorsCytidine TriphosphateProteinsAntiviral AgentsBiosynthetic PathwaysViperin ProteinHEK293 CellsHumansIntramolecular TransferasesResearch ArticleProtein Binding

Sustainable Development Goals

SDG 3: 3. Good health

The antiviral enzyme viperin inhibits cholesterol biosynthesis

FAIR Checklist

Authors (10)

Funding (10 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)