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Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100828Source: DataRank Database

Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 18 times.

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Open Access18 citations

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Enrichment:Funding (7 grants)Impact (FWCI 1.17)OA: goldTopics (118)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Alan M. O’Neill ORCID,Tatsuya Dokoshi ORCID,Elizabeth Wei-Chia Luo ORCID,Gerard C. L. Wong ORCID,Richard L. Gallo ORCID

Live enrichment

PubMed:34048712 PMC:PMC8214221 OpenAlex:https://openalex.org/W3165780018

National Institutes of Health

Grant: R37AI052453

NIDDK NIH HHS

Grant: R01 DK128787

NIAID NIH HHS

Grant: R01 AI153185

NIAMS NIH HHS

Grant: R01 AR076082

National Institutes of Health

Grant: 1R01AI153185-01

Quorum sensing, diversity and skin inflammation

National Institutes of Health

Grant: 1R01AR076082-01

Conflict and Cooperation between AMP Species on the skin

National Institutes of Health

Grant: 5R37AI052453-19

Cathelicidin in Skin Immunity

FWCI

1.17

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925821006268/pdf

publisherhttp://www.jbc.org/article/S0021925821006268/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925821006268?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925821006268?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2021.100828

Fields of Study

Antimicrobial Peptides and ActivitiesToxin Mechanisms and ImmunotoxinsInvertebrate Immune Response Mechanisms0301 basic medicine0302 clinical medicine03 medical and health sciencesAlanineAmino Acid SequenceAnimalsAntimicrobial Cationic PeptidesBiophysical PhenomenaCell LineCell MembraneCytokinesFemaleGene Expression RegulationHumansImmunity, InnateInflammationInterferon Type IMice, Inbred C57BLMutationProtein BindingRNA, Double-StrandedReceptors, ScavengerSignal TransductionStructure-Activity RelationshipToll-Like Receptor 3Transcription, GeneticCathelicidinsMice

MeSH Terms

AlanineAmino Acid SequenceAnimalsCell LineCell MembraneFemaleGene Expression RegulationHumansImmunity, InnateInflammationInterferon Type IMice, Inbred C57BLMutationProtein BindingRNA, Double-StrandedStructure-Activity RelationshipTranscription, GeneticSignal TransductionCytokinesAntimicrobial Cationic PeptidesReceptors, ScavengerToll-Like Receptor 3MiceCathelicidinsBiophysical Phenomena

Keywords

Scavenger receptorCathelicidinInflammationReceptorSequence (biology)RNAScavengerPresentation (obstetrics)ChemistryBiologyBiochemistryCell biologyImmunologyInnate immune systemMedicineGeneAntioxidantCytokinesInterferonSKinAntimicrobial peptidesBiomedical and clinical sciencesInbred C57BLMedical and Health SciencesMiceDouble-StrandedReceptorsInnateReceptors, ScavengerAlanineBiological SciencesInfectious DiseasesInterferon Type IFemaleTranscriptionResearch ArticleProtein BindingSignal Transduction570Biochemistry & Molecular Biology610Biophysical PhenomenaCell LineStructure-Activity RelationshipGeneticCathelicidinsGeneticsAnimalsHumansAmino Acid SequenceRNA, Double-StrandedCell MembraneImmunityImmunity, InnateToll-Like Receptor 3Mice, Inbred C57BLEmerging Infectious DiseasesChemical sciencesGene Expression RegulationMutationBiochemistry and Cell BiologyAntimicrobial Cationic Peptides

Sustainable Development Goals

SDG 3: 3. Good health

Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors

FAIR Checklist

Authors (6)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)