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A thiol-based intramolecular redox switch in four-repeat tau controls fibril assembly and disassembly

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101021Source: DataRank Database

A thiol-based intramolecular redox switch in four-repeat tau controls fibril assembly and disassembly is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 20 times.

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Open Access20 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: goldTopics (25)IDs (PubMed, PMC)SDGs (1)

FAIR Checklist

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Tyler J. Holub,Brad J. Krzesinski,Martin Margittai ORCID,Hilary A. Weismiller

Live enrichment

PubMed:34339733 PMC:PMC8387771

National Institutes of Health

Grant: RF1AG061566

National Institutes of Health

Grant: 7RF1AG061566-02

Tau pathology in Down syndrome and Alzheimer's

goldLicense: cc-by

publisherhttp://www.jbc.org/article/S0021925821008231/pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8387771

Europe_PMChttps://europepmc.org/articles/PMC8387771

Europe_PMChttps://europepmc.org/articles/PMC8387771?pdf=render

https://doi.org/10.1016/j.jbc.2021.101021

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Alzheimer DiseaseSulfhydryl Compoundstau ProteinsProtein IsoformsOxidation-Reduction

Keywords

AmyloidAggregationAlzheimer's diseaseThiolPriontau ProteinFibrilDisulfideconformationRedox SwitchSeeding BarrierAlzheimer DiseaseProtein Isoformstau ProteinsSulfhydryl CompoundsOxidation-ReductionResearch Article

Sustainable Development Goals

SDG 3: 3. Good health