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Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101033Source: DataRank Database

Efficient killing of tumor cells by CAR-T cells requires greater number of engaged CARs than TCRs is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 28 times.

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Open Access28 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: goldTopics (19)IDs (PubMed, PMC)

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Authors (6)

S. S. Panteleev ORCID,Nicholas William Mazzanti,Mizue Terai ORCID,Takami Sato ORCID,Yuri Sykulev ORCID

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PubMed:34371020 PMC:PMC8452787

National Institutes of Health

Thomas Jefferson University

goldLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.jbc.2021.101033

publisherhttps://api.elsevier.com/content/article/PII:S0021925821008358?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925821008358?httpAccept=text/plain

repositoryhttps://jdc.jefferson.edu/mifp/134

repositoryhttp://europepmc.org/pmc/articles/PMC8452787

MeSH Terms

CD8-Positive T-LymphocytesCell Line, TumorHumansMelanomaReceptors, Antigen, T-CellAntigens, NeoplasmHLA-A2 AntigenImmunotherapy, AdoptiveLymphocyte ActivationCell DeathReceptors, Chimeric AntigenChondroitin Sulfate Proteoglycan 4

Keywords

Immunotherapytumor immunologyT-cell Receptor (Tcr)Receptor RegulationChimeric Antigen Receptor (Car)Killing Efficiency Of Various Melanoma Cells By Car- Or Tcr-triggered T-cellsT-cell Bioengineering