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Alkaline intracellular pH (pHi) activates AMPK–mTORC2 signaling to promote cell survival during growth factor limitation

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101100Source: DataRank Database

Alkaline intracellular pH (pHi) activates AMPK–mTORC2 signaling to promote cell survival during growth factor limitation is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 33 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access33 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.93)OA: goldTopics (41)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Stephen I. Lentz ORCID,Diane C. Fingar ORCID,Dubek Kazyken ORCID

Live enrichment

PubMed:34418433 PMC:PMC8479482 OpenAlex:https://openalex.org/W3194001075

Michigan Diabetes Research Center, University of Michigan

Grant: NIH-P30-DK020572

NIGMS NIH HHS

Grant: R01 GM137577

NIDDK NIH HHS

Grant: R01 DK103877

NIDDK NIH HHS

Grant: P30 DK020572

National Institutes of Health

FWCI

1.93

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925821009030/pdf

publisherhttp://www.jbc.org/article/S0021925821009030/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925821009030?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925821009030?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2021.101100

Fields of Study

PI3K/AKT/mTOR signaling in cancerCancer, Hypoxia, and MetabolismMetabolism, Diabetes, and CancerAMP-Activated Protein KinasesAnimalsApoptosisCell SurvivalHEK293 CellsHumansHydrogen-Ion ConcentrationIntercellular Signaling Peptides and ProteinsMechanistic Target of Rapamycin Complex 2MiceSignal Transduction

MeSH Terms

Mechanistic Target of Rapamycin Complex 2AnimalsCell SurvivalHumansHydrogen-Ion ConcentrationSignal TransductionApoptosisIntercellular Signaling Peptides and ProteinsMiceAMP-Activated Protein KinasesHEK293 Cells

Keywords

mTORC2AMPKPI3K/AKT/mTOR pathwaymTORC1Protein kinase BSignal transductionCell growthCell biologyBiologyChemistryProtein kinase ACancer researchBiochemistryKinaseAKTIntracellular Ph (Phi)

Sustainable Development Goals

SDG 0: Good health and well-being

Alkaline intracellular pH (pHi) activates AMPK–mTORC2 signaling to promote cell survival during growth factor limitation

FAIR Checklist

Authors (3)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)