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The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101174Source: DataRank Database

The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0.621. It has been cited 62 times.

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0.621DataRank · unranked

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Open Access62 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)Impact (FWCI 3.33)OA: goldTopics (70)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.621

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (16)

Scott M. Emrich ORCID,Xuexin Zhang,Ping Xin,Vikas Arige ORCID,Trayambak Pathak ORCID

Live enrichment

PubMed:34499925 PMC:PMC8496184 OpenAlex:https://openalex.org/W3198444904

National Heart Lung and Blood Institute

Grant: R35-HL150778

NCI

Grant: R01 CA242021

NIDCR

Grant: R01 DE019245

NIDCR

Grant: R01 HL137852

NHLBI NIH HHS

Grant: R35 HL150778

National Institutes of Health

Grant: 5R01CA242021-05

Regulation of mitochondrial redox homeostasis and signaling in metastatic ovarian cancer

National Institutes of Health

Grant: 5R01HL137852-02

Structural Basis of Peripheral Coupling Sites Regulating Arterial Smooth Muscle Contractility (A1)

National Institutes of Health

Grant: 7R35HL150778-03

Ca2+ signaling Networks in Health and Disease

National Institutes of Health

Grant: 5R01DE019245-08

An experimental/computational approach for understanding salivary fluid secretion

National Institutes of Health

National Institute of Diabetes and Digestive and Kidney Diseases

FWCI

3.33

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925821009765/pdf

publisherhttp://www.jbc.org/article/S0021925821009765/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925821009765?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925821009765?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2021.101174

Fields of Study

Mitochondrial Function and PathologyIon channel regulation and functionATP Synthase and ATPases Research0303 health sciences03 medical and health sciencesCRISPR-Cas SystemsCalciumCalcium ChannelsCalcium SignalingCytosolEndoplasmic ReticulumGene Knockout TechniquesHCT116 CellsHEK293 CellsHumansJurkat CellsLymphocyte ActivationMitochondriaNFATC Transcription FactorsT-Lymphocytes

MeSH Terms

CalciumCytosolEndoplasmic ReticulumHumansLymphocyte ActivationMitochondriaT-LymphocytesCalcium ChannelsJurkat CellsCalcium SignalingHCT116 CellsNFATC Transcription FactorsGene Knockout TechniquesHEK293 CellsCRISPR-Cas Systems

Keywords

UniporterNFATRegulatorCell biologyChemistryMitochondrionBiophysicsBiologyCytosolBiochemistryTranscription factorEnzymeGeneMitochondriaCalcium signalingCalcium OscillationsSoceCrac ChannelsMcuNFATC Transcription FactorsBiochimieT-LymphocytesBiologie moléculaireEndoplasmic ReticulumHCT116 CellsLymphocyte ActivationGene Knockout TechniquesJurkat CellsHEK293 CellsHumansBiologie cellulaireCalciumCalcium ChannelsCRISPR-Cas SystemsResearch Article

Sustainable Development Goals

SDG 0: Responsible consumption and production

Additional file 1 of Spatial and single-cell explorations uncover prognostic significance and immunological functions of mitochondrial calcium uniporter in breast cancer

10.6084/m9.figshare.26708207.v1figshare

Additional file 1 of Spatial and single-cell explorations uncover prognostic significance and immunological functions of mitochondrial calcium uniporter in breast cancer

10.6084/m9.figshare.26708207figshare

The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation

FAIR Checklist

DataRank Breakdown

Authors (16)

Funding (11 grants)

Impact

Open Access

Topics

Linked Datasets (2)

Annotations (Europe PMC)