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The sialidase NEU1 directly interacts with the juxtamembranous segment of the cytoplasmic domain of mucin-1 to inhibit downstream PI3K-Akt signaling

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101337Source: DataRank Database

The sialidase NEU1 directly interacts with the juxtamembranous segment of the cytoplasmic domain of mucin-1 to inhibit downstream PI3K-Akt signaling is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Open Access10 citations

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Enrichment:Funding (2 grants)OA: goldTopics (18)IDs (PubMed, PMC)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Akihiro Imamura ORCID,Hideharu Ishida ORCID,Kurt H. Piepenbrink ORCID,Simeon E. Goldblum,Erik P. Lillehoj ORCID

Live enrichment

PubMed:34688655 PMC:PMC8591358

NIAID NIH HHS

Grant: R21 AI144497

National Institutes of Health

goldLicense: cc-by

publisherhttps://doi.org/10.1016/j.jbc.2021.101337

publisherhttps://api.elsevier.com/content/article/PII:S0021925821011431?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925821011431?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8591358

Europe_PMChttps://europepmc.org/articles/PMC8591358

MeSH Terms

HumansNeuraminidaseAmino Acid SubstitutionSignal TransductionMutation, MissenseProto-Oncogene Proteins c-aktMucin-1Phosphatidylinositol 3-KinasesHEK293 CellsProtein DomainsA549 Cells

Keywords

Sialic acidSialidaseMucin 1Neuraminidase-1Phosphatidylinositide 3-Kinase (Pi 3-Kinase)Cell Surface Associated (Muc1)Akt Pbk