Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102225Source: DataRank Database

Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 19 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access19 citations

Free full text

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 1.01)OA: goldTopics (57)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (13)

Mark Perfetto ORCID,Congyu Lu ORCID,Minghui Zhuo,Harinath Bahudhanapati,Jiejing Li ORCID

Live enrichment

PubMed:35780836 OpenAlex:https://openalex.org/W4283745615

NIGMS

Grant: P20 GM104316

NIGMS

Grant: R01 GM114105

NIGMS

Grant: R35 GM133560

NIGMS

Grant: U54 GM104941

NIDCR

Grant: R01 DE029802

National Institutes of Health

Grant: 5R01GM114105-04

A conserved ADAM-ephrin-Wnt signaling axis in neural crest development and cancer

National Institutes of Health

Grant: 4U54GM104941-04

Delaware - CTR

National Institutes of Health

Grant: 3P20GM104316-10S1

Discovery of Molecular Probes and Therapeutic Leads

National Institutes of Health

Grant: 1R01DE029802-01

Mechanisms of Neural Crest Induction and Craniofacial Disorders

National Institutes of Health

Grant: 1R35GM133560-01

Regulation of heme synthesis by mitochondrial proteins

FWCI

1.01

Citation Percentile

0.7%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.jbc.2022.102225

publisherhttps://doi.org/10.1016/j.jbc.2022.102225

publisherhttps://api.elsevier.com/content/article/PII:S0021925822006676?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925822006676?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35780836

Fields of Study

Axon Guidance and Neuronal SignalingCancer-related gene regulationWnt/β-catenin signaling in development and cancer0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsCell MovementHumansLigandsMammalsMembrane ProteinsColorectal NeoplasmsEphrinsMetalloproteasesCell Line, TumorCell ProliferationProto-Oncogene Proteins c-aktADAM ProteinsTOR Serine-Threonine KinasesWnt Signaling Pathway

Keywords

Protein kinase BPI3K/AKT/mTOR pathwayWnt signaling pathwayDownstream (manufacturing)MetalloproteinaseCancer researchColorectal cancerChemistryCell biologyIκB kinaseKinaseErythropoietin-producing hepatocellular (Eph) receptorSignal transductionBiologyCancerMatrix metalloproteinaseBiochemistryNF-κBGeneticsBusinessReceptor tyrosine kinaseMammalsAccelerated CommunicationTOR Serine-Threonine KinasesMembrane ProteinsLigandsADAM ProteinsCell MovementCell Line, TumorMetalloproteasesAnimalsHumansColorectal NeoplasmsEphrinsProto-Oncogene Proteins c-aktCell Proliferation

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being