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The N-linker region of hERG1a upregulates hERG1b potassium channels

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102233Source: DataRank Database

The N-linker region of hERG1a upregulates hERG1b potassium channels is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 0.46)OA: goldTopics (52)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Taylor Crawford,Matthew C. Trudeau ORCID,Ashley A. Johnson ORCID

Live enrichment

PubMed:35798139 PMC:PMC9428852 OpenAlex:https://openalex.org/W4283821516

National Heart, Lung, and Blood Institute

Grant: F32 HL131189-01

National Institute of General Medical Sciences

Grant: R01 GM127523

National Institute of General Medical Sciences

Grant: R01 GM130701

National Institute of General Medical Sciences

Grant: T32 008181

NIGMS NIH HHS

Grant: T32 GM008181

NHLBI NIH HHS

Grant: F32 HL131189

National Institutes of Health

Grant: 5R01GM127523-02

Regulatory and Functional Mechanisms in hERG Ion Channels

National Institutes of Health

Grant: 1F32HL131189-01

The F-actin binding protein TRIOBP-1 regulates hERG K+ channels

National Institutes of Health

Grant: 1R01GM130701-01

Conformational Dynamics of hERG Potassium Channels

National Institutes of Health

FWCI

0.46

Citation Percentile

0.6%

Citation Trend

2023

2024

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925822006755/pdf

publisherhttp://www.jbc.org/article/S0021925822006755/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925822006755?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925822006755?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2022.102233

Fields of Study

Cardiac electrophysiology and arrhythmiasIon channel regulation and functionReceptor Mechanisms and Signaling0301 basic medicine0303 health sciences03 medical and health sciencesAlanineBiotinEther-A-Go-Go Potassium ChannelsHumansLong QT SyndromeMutagenesisProtein DomainsUp-Regulation

MeSH Terms

Protein DomainsAlanineBiotinHumansLong QT SyndromeUp-RegulationMutagenesisEther-A-Go-Go Potassium Channels

Keywords

Potassium channelLinkerhERGMutagenesisMutantChemistryCell biologyDownregulation and upregulationBiotinylationBiophysicsAmino acidBiologyBiochemistryGeneFRETLong QT syndromeKCNH2Pas DomainEag DomainHerg1bHerg1aBiochemical Pull-down Interaction AssayN-linker DomainAlanineProtein DomainsBiotinHumansEther-A-Go-Go Potassium ChannelsResearch ArticleUp-Regulation

Sustainable Development Goals

SDG 0: Good health and well-being