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The 5′-phosphate enhances the DNA-binding and exonuclease activities of human mitochondrial genome maintenance exonuclease 1 (MGME1)

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102306Source: DataRank Database

The 5′-phosphate enhances the DNA-binding and exonuclease activities of human mitochondrial genome maintenance exonuclease 1 (MGME1) is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 6 times.

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Open Access6 citations

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Enrichment:Funding (2 grants)OA: goldTopics (40)IDs (PubMed, PMC)Annotations (1)

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Authors (3)

Wenyan Xu ORCID,Linlin Zhao ORCID,Kathleen M. Urrutia ORCID

Live enrichment

PubMed:35934053 PMC:PMC9460513

National Institutes of Health

Grant: R35 GM128854

National Institutes of Health

Grant: 7R35GM128854-02

Chemical and Molecular Mechanisms of Mitochondrial DNA Degradation

goldLicense: CC BY

publisherhttps://api.elsevier.com/content/article/PII:S0021925822007487?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925822007487?httpAccept=text/plain

Europe_PMChttps://europepmc.org/articles/PMC9460513

Europe_PMChttps://europepmc.org/articles/PMC9460513?pdf=render

https://doi.org/10.1016/j.jbc.2022.102306

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansPhosphatesExodeoxyribonucleasesPhosphodiesterase IDNA, MitochondrialDNA, Single-StrandedDNA RepairGenome, MitochondrialDNA Polymerase gamma

Keywords

DNA damageDNA repairMitochondrial DNADna EnzymeDna Turnover570Biochemistry & Molecular Biology1.1 Normal biological development and functioning610DNA, Single-StrandedMedical and Health SciencesDNA, MitochondrialPhosphatesSingle-StrandedUnderpinning researchGeneticsHumansGenomeDNABiological SciencesMitochondrialDNA Polymerase gammaExodeoxyribonucleasesPhosphodiesterase IChemical SciencesGenome, MitochondrialGeneric health relevanceResearch Article