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The heme-regulated inhibitor kinase requires dimerization for heme-sensing activity

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102451Source: DataRank Database

The heme-regulated inhibitor kinase requires dimerization for heme-sensing activity is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 20 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access20 citations

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Linked data & code

uniprot

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 1.91)OA: goldTopics (31)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Ryan P. Emptage ORCID,Gerd A. Blobel ORCID,Ronen Marmorstein ORCID,M. Daniel Ricketts

Live enrichment

PubMed:36063997 PMC:PMC9520036 OpenAlex:https://openalex.org/W4294549679

National Institutes of Health

Grant: P01 AG031862

National Institutes of Health

Grant: R01 CA226888

National Institutes of Health

Grant: R01HL119479

National Institutes of Health

Grant: T32 CA115299

National Institutes of Health

Grant: T32 DK007780

Abramson Family Cancer Research Institute

Perelman School of Medicine, University of Pennsylvania

FWCI

1.91

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.jbc.2022.102451

publisherhttps://doi.org/10.1016/j.jbc.2022.102451

publisherhttps://api.elsevier.com/content/article/PII:S0021925822008948?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925822008948?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36063997

Fields of Study

Hemoglobinopathies and Related DisordersErythrocyte Function and PathophysiologyIron Metabolism and Disorders

MeSH Terms

HemeHumansKineticsPhosphorylationProtein BindingEukaryotic Initiation Factor-2DimerizationeIF-2 Kinase

Keywords

AutophosphorylationHemeGlobinBiochemistryKinaseCell biologyChemistryProtein kinase ABiologyHemoglobinEnzymeBiophysicsβ-thalassemiaProtein DimerizationHeme BindingHeme-regulated InhibitorΒ-hemoglobinopathiesEif2α PhosphorylationHeme RegulationGlobin Translation

The heme-regulated inhibitor kinase requires dimerization for heme-sensing activity

FAIR Checklist

Authors (4)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)