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Glucocorticoid receptor dysregulation underlies 5-HT2AR-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102481Source: DataRank Database

Glucocorticoid receptor dysregulation underlies 5-HT2AR-dependent synaptic and behavioral deficits in a mouse neurodevelopmental disorder model is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Open Access8 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)Impact (FWCI 0.31)OA: goldTopics (63)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Carolina Muguruza ORCID,Salvador Sierra ORCID,José L. Moreno ORCID,Luís F. Callado ORCID,J. Javier Meana ORCID

Live enrichment

PubMed:36100039 PMC:PMC9589215 OpenAlex:https://openalex.org/W4295242255

National Institutes of Health

Grant: F30MH116550

National Institutes of Health

Grant: NIH-N01DA-17-8932

National Institutes of Health

Grant: NIH-N01DA-19-8949

National Institutes of Health

Grant: R01MH084894

National Institutes of Health

Grant: R01MH111940

Eusko Jaurlaritza

Grant: IT1211-19

National Institutes of Health

Grant: 2R01MH084894-10

Structure and function of GPCR heteromeric complexes in brain

National Institutes of Health

Grant: 5R01MH111940-02

Preclinical role of HDAC2 in mGlu2-dependent schizophrenia treatment

National Institutes of Health

Grant: 5F30MH116550-04

Gut dysbiosis and 5-HT2A dysregulation in a preclinical schizophrenia model

FWCI

0.31

Citation Percentile

0.4%

Influential Citations

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.jbc.2022.102481

GREENhttp://addi.ehu.es/bitstream/10810/58283/1/1-s2.0-S0021925822009243-main.pdf

publisherhttps://doi.org/10.1016/j.jbc.2022.102481

publisherhttps://api.elsevier.com/content/article/PII:S0021925822009243?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925822009243?httpAccept=text/plain

Fields of Study

Tryptophan and brain disordersNeuroendocrine regulation and behaviorStress Responses and CortisolBiologyMedicineEnvironmental Science0301 basic medicine0303 health sciences03 medical and health sciencesPregnancyFemaleMiceHumansAnimalsSerotoninReceptors, GlucocorticoidDisease Models, AnimalNeurodevelopmental DisordersSchizophreniaReceptor, Serotonin, 5-HT2A

MeSH Terms

AnimalsDisease Models, AnimalFemaleHumansPregnancyReceptors, GlucocorticoidSchizophreniaSerotoninReceptor, Serotonin, 5-HT2AMiceNeurodevelopmental Disorders

Keywords

Dendritic spineNeuroscienceOffspringDownregulation and upregulationSchizophrenia (object-oriented programming)Prefrontal cortexCortex (anatomy)BiologyMedicinePregnancyHippocampal formationGeneticsPsychiatryCognitionSchizophreniaGlucocorticoid receptorDendritic SpinesMaternal Immune ActivationG Protein–coupled ReceptorSerotonin 5-Ht(2a) ReceptorNeurodevelopmental Psychiatric ConditionsSerotoninMiceDisease Models, AnimalReceptors, GlucocorticoidNeurodevelopmental Disordersserotonin 5-HT2A receptorHumansAnimalsFemaleReceptor, Serotonin, 5-HT2AResearch Article

Sustainable Development Goals

SDG 3: 3. Good health