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Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102538Source: DataRank Database

Enhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890 is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 6 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (22 grants)Impact (FWCI 0.39)OA: goldTopics (40)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Morgan B. Dwyer,Jenna Aumiller ORCID,Alethia J Dixon ORCID,Asuka Inoue ORCID,Patrick Osei‐Owusu ORCID

Live enrichment

PubMed:36174676 PMC:PMC9626947 OpenAlex:https://openalex.org/W4297399275

National Institutes of Health

Grant: R01 GM138943 R01 GM56444

National Institutes of Health

Grant: R01 HL139754

American Heart Association

Grant: JP20am0101095

American Heart Association

Grant: 20gm0010004

American Heart Association

Grant: 16SDG27260276

Japan Science and Technology Agency International Cooperative Research Project ATP Synthesis Regulation Project

Grant: JPMJFR215T

Japan Society for the Promotion of Science

Grant: 21H04791

NIGMS NIH HHS

Grant: R01 GM138943

NIGMS NIH HHS

Grant: R01 GM056444

NCI NIH HHS

Grant: F31 CA224803

NIGMS NIH HHS

Grant: T32 GM100836

National Institutes of Health

Grant: 5F31CA224803-02

Understanding G alpha q/11 localization and trafficking in uveal melanoma

National Institutes of Health

Grant: 1R01HL139754-01

In Vivo Mechanisms of Integrated G protein Signaling Regulation by RGS Proteins

National Institutes of Health

Grant: 4R01GM056444-17

Membrane Targeting of G Proteins

National Institutes of Health

Grant: 5T32GM100836-02

Training Program in Cellular, Biochemical, and Molecular Sciences

National Institutes of Health

Grant: 5R01GM138943-02

Regulation of Mutationally Activated Gq/11

Daiichi Sankyo Foundation of Life Science

Tokyo Biochemical Research Foundation

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Thomas Jefferson University

Uehara Memorial Foundation

FWCI

0.39

Citation Percentile

0.5%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925822009814/pdf

publisherhttp://www.jbc.org/article/S0021925822009814/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925822009814?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925822009814?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2022.102538

Fields of Study

Retinal Development and DisordersReceptor Mechanisms and SignalingOcular Oncology and Treatments0301 basic medicine0303 health sciences03 medical and health sciencesCell MembranePeptides, CyclicProtein BindingSignal TransductionGTP-Binding Protein alpha Subunits, Gq-G11Receptors, G-Protein-Coupled

MeSH Terms

Cell MembranePeptides, CyclicProtein BindingSignal TransductionReceptors, G-Protein-CoupledGTP-Binding Protein alpha Subunits, Gq-G11

Keywords

ChemistryMolecular biologyCell biologyBiologyOncogenePlasma membraneGTPaseheterotrimeric G proteinCell signalingProtein TargetingProtein Acylation570Medical SciencesCell MembraneMedical BiochemistryPeptides, CyclicReceptors, G-Protein-CoupledMedicine and Health SciencesGTP-Binding Protein alpha Subunits, Gq-G11Research ArticleProtein BindingSignal Transduction

Sustainable Development Goals

SDG 0: Decent work and economic growth