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Neurodegeneration risk factor, EIF2AK3 (PERK), influences tau protein aggregation

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102821Source: DataRank Database

Neurodegeneration risk factor, EIF2AK3 (PERK), influences tau protein aggregation is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 27 times.

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Open Access27 citations

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Enrichment:Funding (7 grants)OA: goldTopics (55)IDs (PubMed, PMC)Annotations (4)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Ke Xu ORCID,Leon Chea,Kyle Kim,Lance A. Safarta,Keon‐Hyoung Song

Live enrichment

PubMed:36563857 PMC:PMC9852698

NIH

Grant: R01NS088485

Department of Veterans Affairs

Grant: I01RX002340

BLRD VA

Grant: I01 BX002284

National Institutes of Health

Grant: 5I01RX002340-08

Endoplasmic Reticulum Stress in Neurodegeneration

National Institutes of Health

Grant: 3R01NS088485-07S1

Protein Homeostasis and Proteotoxicity Mechanisms

Soonchunhyang University

American Federation for Aging Research

goldLicense: cc-by

publisherhttps://doi.org/10.1016/j.jbc.2022.102821

publisherhttps://api.elsevier.com/content/article/PII:S0021925822012649?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925822012649?httpAccept=text/plain

repositoryhttps://escholarship.org/content/qt98r0v8r3/qt98r0v8r3.pdf?t=rxm3cw

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9852698

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansTauopathiesDisease SusceptibilityeIF-2 Kinasetau ProteinsRisk FactorsMutationProtein AggregatesProtein Aggregation, Pathological

Keywords

NeurodegenerationUnfolded protein responseintegrated stress responseER stressTauopathypERKEif2ak3Tau AggregationEif2α PhosphorylationAgingBiochemistry & Molecular BiologyBiomedical and clinical sciences610tau ProteinsNeurodegenerativeAlzheimer's DiseaseMedical and Health SciencesProtein Aggregation, PathologicaleIF-2 KinaseProtein AggregatesPathologicalRisk FactorsAcquired Cognitive ImpairmentGenetics2.1 Biological and endogenous factorsHumansAetiologyAlzheimer's Disease Related Dementias (ADRD)PreventionNeurosciencesAlzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)Biological SciencesProtein AggregationBrain DisordersFrontotemporal Dementia (FTD)Chemical sciencesTauopathiesNeurologicalMutationDementiaBiochemistry and Cell BiologyDisease SusceptibilityResearch Article

Sustainable Development Goals

SDG 3: 3. Good health

Neurodegeneration risk factor, EIF2AK3 (PERK), influences tau protein aggregation

FAIR Checklist

Authors (12)

Funding (7 grants)

Open Access

Topics

Annotations (Europe PMC)