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Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.102875Source: DataRank Database

Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)OA: goldTopics (24)IDs (PubMed)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Cheng‐Hsun Chen,Katelyn O’Neill,Valerie J. Fousek-Schuller ORCID,Adrian R. Black ORCID,Jennifer D. Black ORCID

Live enrichment

PubMed:36621626

National Institutes of Health

Grant: R01GM118437

National Institutes of Health

Grant: R03CA205496

National Institutes of Health

Grant: 5R01GM118437-03

Mechanism of Bax/Bak Activation During Apoptosis

National Institutes of Health

Grant: 1R03CA205496-01A1

Bax/Bak activation without direct activator BH3-only proteins in cancer cells

goldLicense: cc-by

publisherhttp://www.jbc.org/article/S0021925823000078/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925823000078?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925823000078?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9922828/pdf/main.pdf

https://doi.org/10.1016/j.jbc.2023.102875

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

SulfonamidesBiphenyl Compoundsbcl-X ProteinAntineoplastic AgentsApoptosisAzepinesHCT116 CellsPiperazinesEnzyme ActivationNitrophenolsProto-Oncogene Proteins c-bcl-2Aurora KinasesCell Line, TumorColonic NeoplasmsBenzamidesHumansMyeloid Cell Leukemia Sequence 1 ProteinPyrazolesApoptosis Regulatory ProteinsResearch Articlebcl-2-Associated X Protein

Sustainable Development Goals

SDG 3: 3. Good health