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Overexpression of Pdx1, reduction of p53, or deletion of CHOP attenuates pancreas hypoplasia in mice with pancreas-specific O-GlcNAc transferase deletion

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.102878Source: DataRank Database

Overexpression of Pdx1, reduction of p53, or deletion of CHOP attenuates pancreas hypoplasia in mice with pancreas-specific O-GlcNAc transferase deletion is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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Enrichment:Funding (6 grants)OA: goldTopics (21)IDs (PubMed, PMC)

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Authors (8)

Samantha K Pritchard ORCID,Mackenzie Moore ORCID,Brian Akhaphong ORCID,Nandini Avula ORCID,Megan Beetch ORCID

Live enrichment

PubMed:36623733 PMC:PMC9932656

NHLBI NIH HHS

Grant: T32 HL166142

NIDDK NIH HHS

Grant: T32 DK108733

NIDDK NIH HHS

Grant: R56 DK136293

NIDDK NIH HHS

Grant: R01 DK115720

NIDDK NIH HHS

Grant: T32 DK007203

NIGMS NIH HHS

Grant: T32 GM140936

goldLicense: cc-by-nc-nd

publisherhttp://www.jbc.org/article/S0021925823000108/pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9932656/pdf/main.pdf

Europe_PMChttps://europepmc.org/articles/PMC9932656

Europe_PMChttps://europepmc.org/articles/PMC9932656?pdf=render

MeSH Terms

Pancreas, ExocrineAnimalsMicePancreatic DiseasesN-AcetylglucosaminyltransferasesHomeodomain ProteinsTrans-ActivatorsGene ExpressionTumor Suppressor Protein p53Glucagon-Secreting CellsTranscription Factor CHOP

Keywords

p53Transcription factorsIsletER stressO-glcnac TransferaseBeta-cellPdx1ChopPancreas DevelopmentO-glcnacylation