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The 5-lipoxygenase/cyclooxygenase-2 cross-over metabolite, hemiketal E2, enhances VEGFR2 activation and promotes angiogenesis

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.103050Source: DataRank Database

The 5-lipoxygenase/cyclooxygenase-2 cross-over metabolite, hemiketal E2, enhances VEGFR2 activation and promotes angiogenesis is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)Impact (FWCI 0.83)OA: goldTopics (41)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Juan Antonio Giménez‐Bastida ORCID,Paula B. Luis ORCID,Sai H. Presley,Robert E. Boer ORCID,Manuel Chiusa ORCID

Live enrichment

PubMed:36813233 PMC:PMC10040730 OpenAlex:https://openalex.org/W4321457876

National Institutes of Health

Grant: 1S10OD021483-01

NCI

Grant: R01CA162433

Japan Society for the Promotion of Science

Grant: JP 22K20570

Japan Society for the Promotion of Science

Grant: JP20H00493

NIGMS

Grant: R01GM076592

NIGMS

Grant: R01GM115722

NIGMS

Grant: R01GM118412

NIGMS

Grant: R35GM144091

NIDDK

Grant: R01DK095761

U.S. Department of Veterans Affairs

Grant: 1I01BX002025-01

American Heart Association

Grant: 16POST30690001

BLRD VA

Grant: IK6 BX005240

BLRD VA

Grant: I01 BX002025

Vanderbilt University

National Center for Advancing Translational Sciences

FWCI

0.83

Citation Percentile

0.7%

Citation Trend

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.jbc.org/article/S0021925823001825/pdf

publisherhttp://www.jbc.org/article/S0021925823001825/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925823001825?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925823001825?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2023.103050

Fields of Study

Angiogenesis and VEGF in CancerInflammatory mediators and NSAID effectsEicosanoids and Hypertension Pharmacology

MeSH Terms

AnimalsArachidonate 5-LipoxygenaseCell MovementHumansArachidonic AcidNeovascularization, PhysiologicAngiogenesis InhibitorsVascular Endothelial Growth Factor Receptor-2Vascular Endothelial Growth Factor ACell ProliferationMiceCyclooxygenase 2Human Umbilical Vein Endothelial Cells

Keywords

AngiogenesisCell biologyEndothelial stem cellVascular endothelial growth factorBiochemistryBiologyProtein kinase BIn vivoPhosphorylationHuman umbilical vein endothelial cellKinase insert domain receptorSignal transductionArachidonic acidMAPK/ERK pathwayChemistryVascular endothelial growth factor ACancer researchIn vitroEnzymeEicosanoid5-lipoxygenaseCyclooxygenase-2Endothelial CellKinase SignalingSponge Assay

Sustainable Development Goals

SDG 0: Good health and well-being