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Stress-induced pseudokinase TRB3 augments IL1β signaling by interacting with Flightless homolog 1

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104803Source: DataRank Database

Stress-induced pseudokinase TRB3 augments IL1β signaling by interacting with Flightless homolog 1 is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Open Access8 citations

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Enrichment:Funding (6 grants)Impact (FWCI 1.04)OA: goldTopics (56)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Rohan K. Humphrey,Akshita Gorantla,Ergeng Hao,Ulupi S. Jhala,Sumati Gonuguntla

Live enrichment

PubMed:37172723 PMC:PMC10432976 OpenAlex:https://openalex.org/W4376598532

National Institutes of Health

Grant: R01DK080147

National Institutes of Health

Grant: R56DK105443

Juvenile Diabetes Research Foundation United States of America

Grant: 2009-303

NIDDK NIH HHS

Grant: R01 DK116038

National Institutes of Health

Grant: 5R01DK080147-03

Signaling Cascades in Regulation of Pancreatic Beta cell mass.

National Institutes of Health

Grant: 5R56DK105443-02

Molecular Mechanisms Regulating Beta Cell Death

FWCI

1.04

Citation Percentile

0.7%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925823018318/pdf

publisherhttp://www.jbc.org/article/S0021925823018318/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925823018318?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925823018318?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2023.104803

Fields of Study

Endoplasmic Reticulum Stress and DiseasePancreatic function and diabetesFOXO transcription factor regulation0301 basic medicine03 medical and health sciences

MeSH Terms

AnimalsCarbazolesEnzyme InhibitorsMicrofilament ProteinsSignal TransductionTranscriptional ActivationTrans-ActivatorsCytokinesNF-kappa BApoptosisCell Cycle ProteinsInsulin-Secreting CellsMiceNitric Oxide Synthase Type IIInterleukin-1betaMyeloid Differentiation Factor 88

Keywords

Proinflammatory cytokineCell biologySignal transductionBiologySignal transducing adaptor proteinKinasePhosphorylationInflammationImmunologyiNOSIKKToll-like receptorMyD88NfκbMlk3Pancreatic Β CellsTribblesNos2 Interleukin1Trib3 FliiTranscriptional ActivationInterleukin-1betaMicrofilament ProteinsNF-kappa BCarbazolesNitric Oxide Synthase Type IICell Cycle ProteinsApoptosisMiceInsulin-Secreting CellsMyeloid Differentiation Factor 88Trans-ActivatorsAnimalsCytokinesEnzyme InhibitorsResearch Article

Sustainable Development Goals

SDG 0: Good health and well-being

Stress-induced pseudokinase TRB3 augments IL1β signaling by interacting with Flightless homolog 1

FAIR Checklist

Authors (5)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)