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The FAM86 domain of FAM86A confers substrate specificity to promote EEF2-Lys525 methylation

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104842Source: DataRank Database

The FAM86 domain of FAM86A confers substrate specificity to promote EEF2-Lys525 methylation is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0.241. It has been cited 4 times.

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0.241DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)Impact (FWCI 0.37)OA: goldTopics (73)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.241

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (7)

Zengyu Shao ORCID,Pradnya Narkhede ORCID,Annie Truc Trinh ORCID,Jiuwei Lu ORCID,Jikui Song ORCID

Live enrichment

PubMed:37209825 PMC:PMC10285254 OpenAlex:https://openalex.org/W4377103006

NCI

Grant: R01 CA236118

NCI

Grant: F31CA261128

NIGMS

Grant: R35GM119721

NIGMS

Grant: R35 GM139569

NIGMS

Grant: 5T32GM007276

NIGMS

Grant: T32GM120007

NIGMS NIH HHS

Grant: T32 GM139791

NCI NIH HHS

Grant: R01 CA236949

NIGMS NIH HHS

Grant: T32 GM007276

NCI NIH HHS

Grant: R01 CA272844

National Institutes of Health

Grant: 5T32GM007276-36

Cellular and Molecular Biology Training Program

National Institutes of Health

Grant: 5T32GM120007-02

Stanford Chem-H Chemistry/Biology Interface Predoctoral Training Program

National Institutes of Health

Grant: 5R01CA236118-03

Role of the METTL13 Lysine Methyltransferase in Signaling and Cancer

National Institutes of Health

Grant: 1F31CA261128-01A1

Role of the candidate protein methyltransferase METTL18 in cancer biology

National Institutes of Health

Grant: 5R35GM139569-04

Function of Protein Methylation in Chromatin and Signaling Regulation

National Institutes of Health

Grant: 5R35GM119721-02

Mechanistic Insights into Mammalian DNA Methylation

National Institutes of Health

Stanford University

FWCI

0.37

Citation Percentile

0.5%

Citation Trend

2024

2025

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925823018707/pdf

publisherhttp://www.jbc.org/article/S0021925823018707/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925823018707?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925823018707?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2023.104842

Fields of Study

RNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation0301 basic medicine03 medical and health sciencesHumansLysineMethylationMethyltransferasesPeptide Elongation Factor 2S-AdenosylmethionineSubstrate SpecificityProtein DomainsProtein Structure, TertiaryModels, MolecularCrystallography, X-RayPoint Mutation

MeSH Terms

Protein DomainsHumansLysineMethylationMethyltransferasesModels, MolecularS-AdenosylmethionineSubstrate SpecificityPoint MutationProtein Structure, TertiaryCrystallography, X-RayPeptide Elongation Factor 2

Keywords

MethylationDomain (mathematical analysis)Substrate (aquarium)DNA methylationComputational biologyBiologyChemistryCell biologyComputer scienceGeneticsGeneEcologyGene expressionMathematicsProtein synthesisRibosomeMethyltransferaseLysine MethylationTranslation ElongationEef2Mrna TranslationAlphafoldEef2kmtFam86aModels, Molecular570Protein StructureS-Adenosylmethionine610Crystallography, X-RaySubstrate SpecificityPeptide Elongation Factor 2Protein DomainsModelsHumansPoint MutationCrystallographyLysineMolecularMethyltransferasesProtein Structure, TertiaryX-RayTertiaryResearch Article

Sustainable Development Goals

SDG 0: Life in Land