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Identification of small molecules and related targets that modulate tau pathology in a seeded primary neuron model

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104876Source: DataRank Database

Identification of small molecules and related targets that modulate tau pathology in a seeded primary neuron model is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 4 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 0.56)OA: goldTopics (43)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Hailey Gould,Virginia M.‐Y. Lee ORCID,Alex Crowe,Kurt R. Brunden ORCID,Garrett S. Gibbons ORCID

Live enrichment

PubMed:37269953 OpenAlex:https://openalex.org/W4379057273

National Institutes of Health

Grant: P01AG066597

National Institutes of Health

Grant: P30AG072979

National Institutes of Health

Grant: U19AG062418

NIA

Grant: RF1AG066569

National Institutes of Health

Grant: 5P30AG072979-02

Penn Alzheimer's Disease Research Center (ADRC)

National Institutes of Health

Grant: 1RF1AG066569-01

Identification of small molecule inhibitors of tau pathology utilizing a novel primary neuronal assay.

National Institutes of Health

Grant: 5P01AG066597-02

From cells to complex syndromes: using networks to understand heterogeneity in TDP-related frontotemporal degeneration and aging

National Institutes of Health

Grant: 5U19AG062418-02

Center On Alpha-synuclein Strains In Alzheimer Disease & Related Dementias

FWCI

0.56

Citation Percentile

0.6%

Citation Trend

2024

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.jbc.2023.104876

publisherhttps://doi.org/10.1016/j.jbc.2023.104876

publisherhttps://api.elsevier.com/content/article/PII:S002192582301904X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S002192582301904X?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37269953

Fields of Study

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery Methods03 medical and health sciences0302 clinical medicine

MeSH Terms

Alzheimer DiseaseAnimalsHumansNeuronsAmyloid beta-PeptidesAspartic Acid EndopeptidasesAmyloid beta-Protein Precursortau ProteinsRatsAmyloid Precursor Protein Secretases

Keywords

Tau proteinNeurotoxicityTau pathologyChemistryDAPIAmyloid precursor proteinBiochemistryNeuronMolecular biologyAlzheimer's diseaseCell biologyBiologyNeuroscienceToxicityPathologyMedicineDiseaseNeuronsAmyloid beta-Protein PrecursorAmyloid beta-PeptidesAlzheimer DiseaseAnimalsHumansAspartic Acid Endopeptidasestau ProteinsAmyloid Precursor Protein SecretasesResearch ArticleRats

Sustainable Development Goals

SDG 0: Life in Land