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SAMHD1 impairs type I interferon induction through the MAVS, IKKε, and IRF7 signaling axis during viral infection

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104925Source: DataRank Database

SAMHD1 impairs type I interferon induction through the MAVS, IKKε, and IRF7 signaling axis during viral infection is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 13 times.

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Enrichment:Funding (11 grants)OA: goldTopics (32)IDs (PubMed, PMC)Annotations (1)

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Authors (11)

Levent Sari ORCID,Michael P. Cahill ORCID,Hua Yang ORCID,Stacia Phillips ORCID,Nicholas Martinez ORCID

Live enrichment

PubMed:37328105 PMC:PMC10404699

National Institutes of Health

Grant: R01AI130110

National Institutes of Health

Grant: R01AI141495

National Institutes of Health

Grant: R01HL154001

National Institutes of Health

Grant: R01HL157215

National Institutes of Health

Grant: R21AI170070

National Institutes of Health

Grant: R61AI169659

National Institute of Allergy and Infectious Diseases

Grant: ARP-4666

University of Iowa

Grant: IRF7 Δ1/2

National Science Foundation

Grant: DBI-1852070

NHLBI NIH HHS

Grant: R01 HL168501

NIAID NIH HHS

Grant: T32 AI165391

goldLicense: cc-by

GOLDhttp://www.jbc.org/article/S0021925823019531/pdf

publisherhttp://www.jbc.org/article/S0021925823019531/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925823019531?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925823019531?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10404699/pdf/main.pdf

Fields of Study

MedicineBiologyHumansHEK293 CellsI-kappa B KinaseImmunity, InnateInterferon Regulatory Factor-3Interferon Regulatory Factor-7Interferon Type ISAM Domain and HD Domain-Containing Protein 1HIV InfectionsSignal TransductionAdaptor Proteins, Signal Transducing

MeSH Terms

HumansHIV InfectionsAdaptor Proteins, Signal TransducingInterferon Type ISignal TransductionInterferon Regulatory Factor-3Interferon Regulatory Factor-7I-kappa B KinaseImmunity, InnateHEK293 CellsSAM Domain and HD Domain-Containing Protein 1

Keywords

HIV-1InterferonMolecular dockinginnate immunityMavsIrfSamhd1Ikkε

SAMHD1 impairs type I interferon induction through the MAVS, IKKε, and IRF7 signaling axis during viral infection

FAIR Checklist

Authors (11)

Funding (11 grants)

Open Access

Topics

Annotations (Europe PMC)