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Hybrid insulin peptide isomers spontaneously form in pancreatic beta-cells from an aspartic anhydride intermediate

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105264Source: DataRank Database

Hybrid insulin peptide isomers spontaneously form in pancreatic beta-cells from an aspartic anhydride intermediate is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Enrichment:Funding (8 grants)OA: goldTopics (31)IDs (PubMed, PMC)Annotations (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Jason Groegler ORCID,Mylinh Dang,Cole R. Michel ORCID,Roger Powell ORCID,Anita C. Hohenstein ORCID

Live enrichment

PubMed:37734557 PMC:PMC10590738

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01DK119529

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: T32DK120520

NIGMS NIH HHS

Grant: T32 GM008111

NIDDK NIH HHS

Grant: P30 DK116073

National Institutes of Health

Grant: 5T32DK120520-02

Interdisciplinary Bioengineering Research Training in Diabetes

National Institutes of Health

Grant: 5P30DK116073-03

UC Denver Diabetes Research Center

National Institutes of Health

Grant: 5R01DK119529-04

Characterize the Landscape and Origin of Hybrid Peptides in Beta Cells

National Institutes of Health

goldLicense: cc-by

publisherhttp://www.jbc.org/article/S0021925823022925/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925823022925?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925823022925?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10590738/pdf/main.pdf

Europe_PMChttps://europepmc.org/articles/PMC10590738

Fields of Study

0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsHumansMiceDiabetes Mellitus, Type 1InsulinAspartic AcidPeptidesInsulin-Secreting CellsMass SpectrometryIn Vitro Techniques

Keywords

ChromatographyMass spectrometrytype 1 diabetesIslet amyloid polypeptidechromogranin Aautoimmune diseaseAspartate (Aspartic Acid)Beta Cell (Β-cell)Insulin C-peptideMiceAspartic AcidDiabetes Mellitus, Type 1Insulin-Secreting CellsAnimalsHumansInsulinIn Vitro TechniquesPeptidesResearch Article

Hybrid insulin peptide isomers spontaneously form in pancreatic beta-cells from an aspartic anhydride intermediate

FAIR Checklist

Authors (10)

Funding (8 grants)

Open Access

Topics

Annotations (Europe PMC)