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Prioritizing cardiovascular disease-associated variants altering NKX2-5 and TBX5 binding through an integrative computational approach

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105423Source: DataRank Database

Prioritizing cardiovascular disease-associated variants altering NKX2-5 and TBX5 binding through an integrative computational approach is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (8 grants)OA: goldTopics (17)IDs (PubMed, PMC)Annotations (1)

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Reusable (0/3)

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Authors (10)

Diego A. Pomales‐Matos ORCID,Alejandro Rivera-Madera ORCID,Jean L. Messon-Bird ORCID,Joshua G. Medina-Feliciano ORCID,Leandro Sanabria-Alberto ORCID

Live enrichment

PubMed:37926287 PMC:PMC10750078

National Science Foundation

Grant: 1736026

National Institutes of Health

Grant: SC1GM127231

NIGMS NIH HHS

Grant: P20 GM103475

NHGRI NIH HHS

Grant: R25 HG012702

NIGMS NIH HHS

Grant: R25 GM061151

NIGMS NIH HHS

Grant: T34 GM145404

Puerto Rico Science, Technology and Research Trust

University of Puerto Rico

goldLicense: cc-by

publisherhttp://www.jbc.org/article/S0021925823024511/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925823024511?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925823024511?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10750078/pdf/main.pdf

Europe_PMChttps://europepmc.org/articles/PMC10750078

MeSH Terms

Myocytes, CardiacHumansCardiovascular DiseasesGenetic Predisposition to DiseaseT-Box Domain ProteinsTranscription FactorsRegulatory Sequences, Nucleic AcidPolymorphism, Single NucleotideGenome-Wide Association StudyHomeobox Protein Nkx-2.5

Keywords

Gene regulationDNA-binding proteinTranscription factorsGenomicsCardiovascular diseasecomputational biologySingle-nucleotide Polymorphism (Snp)