Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105449Source: DataRank Database

Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 12 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access12 citations

Download PDF

Cite:

Linked data & code

omim pdb

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (13 grants)Impact (FWCI 2.25)OA: goldTopics (55)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (5)

Romila Mascarenhas ORCID,Karanfil Ceric,David P. Ballou ORCID,Ruma Banerjee ORCID,Joseph Roman ORCID

Live enrichment

PubMed:37949228 PMC:PMC10746528 OpenAlex:https://openalex.org/W4388487242

National Institutes of Health

Grant: F32-GM144988

National Institutes of Health

Grant: R35-GM130183

National Institutes of Health

Grant: K99-GM1434820

Argonne National Laboratory

Grant: DE-AC02

Michigan Technology Tri-Corridor

Grant: 085P1000817

NIGMS NIH HHS

Grant: F32 GM144988

NIGMS NIH HHS

Grant: R35 GM130183

NIGMS NIH HHS

Grant: K99 GM143482

National Institutes of Health

Grant: 5R35GM130183-07

Sulfide metabolism and signaling

National Institutes of Health

Grant: 5F32GM144988-02

Allosteric regulation of human cystathionine beta-synthase

U.S. Department of Energy

Michigan Economic Development Corporation

Office of Science

FWCI

2.25

Citation Percentile

0.9%

Citation Trend

2024

2025

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925823024778/pdf

publisherhttp://www.jbc.org/article/S0021925823024778/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925823024778?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925823024778?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2023.105449

Fields of Study

Folate and B Vitamins ResearchSulfur Compounds in BiologyAmino Acid Enzymes and Metabolism0301 basic medicine03 medical and health sciencesHumansAllosteric RegulationCrystallography, X-RayCystathionine beta-SynthaseHomocysteineHomocystinuriaKineticsMutationS-AdenosylmethionineProtein ConformationCatalytic Domain

MeSH Terms

Allosteric RegulationCystathionine beta-SynthaseHomocysteineHomocystinuriaHumansKineticsMutationProtein ConformationS-AdenosylmethionineCrystallography, X-RayCatalytic Domain

Keywords

Cystathionine beta synthaseTranssulfurationAllosteric regulationHomocysteineHomocystinuriaCysteineATP synthaseBiochemistryChemistryMethionine synthaseBiologyEnzymeMethionineHemeHydrogen sulfidePyridoxal phosphateS-AdenosylmethionineCystathionine-β-synthaseAllosteryTranssulfuration PathwayProtein ConformationCystathionine beta-SynthaseCrystallography, X-RayKineticsCatalytic DomainMutationHumansResearch Article

Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation

FAIR Checklist

Authors (5)

Funding (13 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)