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Disruption of lysosomal nutrient sensing scaffold contributes to pathogenesis of a fatal neurodegenerative lysosomal storage disease

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.105641Source: DataRank Database

Disruption of lysosomal nutrient sensing scaffold contributes to pathogenesis of a fatal neurodegenerative lysosomal storage disease is a research paper published in Journal of Biological Chemistry (2024). On theSindex it has a DataRank of 0. It has been cited 6 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 1.47)OA: goldTopics (36)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Abhilash P. Appu ORCID,Tamal Sadhukhan,Avisek Mondal ORCID,Nisha Plavelil,Mahadevan Raghavankutty ORCID

Live enrichment

PubMed:38211816 PMC:PMC10862020 OpenAlex:https://openalex.org/W4390776479

National Institutes of Health

Eunice Kennedy Shriver National Institute of Child Health and Human Development

FWCI

1.47

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925824000176/pdf

publisherhttp://www.jbc.org/article/S0021925824000176/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925824000176?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925824000176?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2024.105641

Fields of Study

Lysosomal Storage Disorders ResearchCalcium signaling and nucleotide metabolismCellular transport and secretion

MeSH Terms

Mechanistic Target of Rapamycin Complex 1AnimalsDisease Models, AnimalLysosomesMammalsMice, Inbred C57BLNeuronal Ceroid-LipofuscinosesThiolester HydrolasesLysosomal Storage DiseasesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktMice

Keywords

PathogenesisLysosomal storage diseaseDiseaseLysosomeScaffoldCell biologySubstrate reduction therapyChemistryBiologyNeuroscienceMedicineBiochemistryImmunologyPathologyBiomedical engineeringEnzyme replacement therapyNeurodegenerationS-palmitoylationIgf1 SignalingCln1 DiseaseMtorc1 Activation

Disruption of lysosomal nutrient sensing scaffold contributes to pathogenesis of a fatal neurodegenerative lysosomal storage disease

FAIR Checklist

Authors (10)

Funding (2 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)