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Homocysteine-induced sustained GluN2A NMDA receptor stimulation leads to mitochondrial ROS generation and neurotoxicity

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107253Source: DataRank Database

Homocysteine-induced sustained GluN2A NMDA receptor stimulation leads to mitochondrial ROS generation and neurotoxicity is a research paper published in Journal of Biological Chemistry (2024). On theSindex it has a DataRank of 0. It has been cited 28 times.

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0DataRank · unranked

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Open Access28 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)OA: goldTopics (36)IDs (PubMed, PMC)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

S. Seelig,Surojit Paul,Ranjana Poddar ORCID,Satya Narayan Deep

Live enrichment

PubMed:38569938 PMC:PMC11081806

National Institute of Neurological Disorders and Stroke

Grant: R01 NS083914

National Institute of Neurological Disorders and Stroke

Grant: R01 NS059962

NIAAA NIH HHS

Grant: R01 AA030309

National Institutes of Health

Grant: 5R01NS059962-15

Role of Brain Specific Tyrosne Phosphatase STEP in Neuroprotection and Death

National Institutes of Health

Grant: 5R01NS083914-08

Molecular basis of hyperhomocysteinemia induced brain injury in ischemic stroke

National Institutes of Health

goldLicense: cc-by

publisherhttp://www.jbc.org/article/S0021925824017502/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925824017502?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925824017502?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11081806/pdf/main.pdf

Europe_PMChttps://europepmc.org/articles/PMC11081806

Fields of Study

03 medical and health sciences0302 clinical medicine

MeSH Terms

NeuronsMitochondriaAnimalsHumansMiceRatsCalciumReactive Oxygen Speciessrc-Family KinasesHomocysteineReceptors, N-Methyl-D-AspartatePhosphorylationFocal Adhesion Kinase 2

Keywords

NeurotoxicityHomocysteinePYK2Mitochondrial Reactive Oxygen SpeciesSrc Family KinaseErk MapkCa(2+) InfluxGlun2a-nmda ReceptorNeuronsReceptors, N-Methyl-D-AspartateMitochondriaRatsMiceFocal Adhesion Kinase 2src-Family KinasesAnimalsHumansCalciumPhosphorylationReactive Oxygen SpeciesResearch Article