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In-depth mapping of DNA-PKcs signaling uncovers noncanonical features of its kinase specificity

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107513Source: DataRank Database

In-depth mapping of DNA-PKcs signaling uncovers noncanonical features of its kinase specificity is a research paper published in Journal of Biological Chemistry (2024). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Enrichment:Funding (3 grants)Impact (FWCI 1.28)OA: goldTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (2)

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Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Marcos V A S Navarro,Carolline F R Ascenҫão,Diego Dibitetto ORCID,Marcus B Smolka,Shannon Marshall

Live enrichment

PubMed:38945450 PMC:PMC11327452 OpenAlex:https://openalex.org/W4400105884

National Institute of General Medical Sciences

Grant: R35GM141159

National Institutes of Health

Grant: 5R35GM141159-03

Signaling Mechanisms in Genome Maintenance

National Institutes of Health

FWCI

1.28

Citation Percentile

0.8%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(24)02014-3/pdf

publisherhttps://www.jbc.org/article/S0021-9258(24)02014-3/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925824020143?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925824020143?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2024.107513

Fields of Study

DNA Repair MechanismsCRISPR and Genetic EngineeringCancer-related Molecular Pathways0301 basic medicine03 medical and health sciencesDNA-Activated Protein KinaseHumansAtaxia Telangiectasia Mutated ProteinsPhosphorylationSignal TransductionSubstrate SpecificityAmino Acid Motifs

MeSH Terms

HumansPhosphorylationSubstrate SpecificitySignal TransductionAmino Acid MotifsDNA-Activated Protein KinaseAtaxia Telangiectasia Mutated Proteins

Keywords

DNA-PKcsCell biologyBiologyPhosphorylationDNA repairDNAKinaseDNA damageSequence motifGeneticsComputational biologyProtein kinase AIonizing RadiationPhosphoproteomicsCellular SignalingDna Damage ResponsePhosphorylation MotifKinase SpecificityDna-dependent Serine/threonine Protein Kinase (Dna-pk)Kinase InterplayAmino Acid MotifsMethods and ResourcesHumansDNA-Activated Protein KinaseAtaxia Telangiectasia Mutated ProteinsSignal TransductionSubstrate Specificity

In-depth mapping of DNA-PKcs signaling uncovers noncanonical features of its kinase specificity

FAIR Checklist

Authors (5)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)