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Virus-like particles as robust tools for functional assessment: Deciphering the pathogenicity of ABCA4 genetic variants of uncertain significance

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107739Source: DataRank Database

Virus-like particles as robust tools for functional assessment: Deciphering the pathogenicity of ABCA4 genetic variants of uncertain significance is a research paper published in Journal of Biological Chemistry (2024). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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Linked data & code

omim refseq

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 0.75)OA: goldTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Subhasis B. Biswas,Arit Ghosh ORCID,Esther E. Biswas ORCID,Senem Cevik ORCID

Live enrichment

PubMed:39222682 PMC:PMC11474199 OpenAlex:https://openalex.org/W4402083895

NEI NIH HHS

Grant: R01 EY036065

NIGMS NIH HHS

Grant: P20 GM103446

National Institutes of Health

Grant: 5P20GM103446-15

Bioinformatics Core

National Institutes of Health

Grant: 1R01EY036065-01

Understanding ABCA4 Variants of Unknown Significance Through Computational and Functional Approaches

Foundation Fighting Blindness Inc

FWCI

0.75

Citation Percentile

0.7%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(24)02240-3/pdf

publisherhttps://www.jbc.org/article/S0021-9258(24)02240-3/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925824022403?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925824022403?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2024.107739

Fields of Study

Virus-based gene therapy researchMonoclonal and Polyclonal Antibodies ResearchRNA and protein synthesis mechanisms0303 health sciences03 medical and health sciencesHumansATP-Binding Cassette TransportersMutation, MissenseGenetic VariationHEK293 CellsVirionAnimals

MeSH Terms

AnimalsHumansGenetic VariationVirionATP-Binding Cassette TransportersMutation, MissenseHEK293 Cells

Keywords

PathogenicityVirusBiologyComputational biologyGeneticsABCA4VirologyGeneMicrobiologyPhenotypeHuman geneticsMembrane proteinGenetic diseaseABC transporterRetinal degenerationPrecision MedicinePathogenicity PredictionVirus-like Particles (Vlps)Variants Of Uncertain Significance (Vus)HEK293 CellsMutation, MissenseVirionHumansGenetic VariationAnimalsATP-Binding Cassette TransportersResearch Article