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PTEN loss in glioma cell lines leads to increased extracellular vesicle biogenesis and PD-L1 cargo in a PI3K-dependent manner

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.108143Source: DataRank Database

PTEN loss in glioma cell lines leads to increased extracellular vesicle biogenesis and PD-L1 cargo in a PI3K-dependent manner is a research paper published in Journal of Biological Chemistry (2024). On theSindex it has a DataRank of 0. It has been cited 10 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access10 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)Impact (FWCI 1.56)OA: goldTopics (59)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Timothy M. Pierpont,Dariana Argueta-Zamora,Kristin Wilson,Avery August ORCID,Richard A. Cerione ORCID

Live enrichment

PubMed:39732171 PMC:PMC11791317 OpenAlex:https://openalex.org/W4405801985

National Institute of General Medical Sciences

Grant: 1R35GM152206-01

Studies of Global Signal Transduction

National Science Foundation

Grant: NNCI-2025233

National Institutes of Health National Cancer Institute

Grant: R01CA201402

NIGMS NIH HHS

Grant: R35 GM152206

National Science Foundation

Grant: 2025233

NNCI: Cornell NanoScale Science and Technology Facility (CNF)

National Institutes of Health

Grant: 5R01CA201402-07

The unique roles of the GTP-binding/protein crosslinking enzyme transglutaminase-2 and signaling partners in aggressive cancers

National Institutes of Health

Alfred P. Sloan Foundation

FWCI

1.56

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(24)02645-0/pdf

publisherhttps://www.jbc.org/article/S0021-9258(24)02645-0/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925824026450?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925824026450?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2024.108143

Fields of Study

Extracellular vesicles in diseaseRNA regulation and diseaseCancer-related molecular mechanisms researchPTEN PhosphohydrolaseB7-H1 AntigenHumansExtracellular VesiclesPhosphatidylinositol 3-KinasesGliomaCell Line, TumorSignal TransductionTumor MicroenvironmentInterferon-gammaAnimals

MeSH Terms

Extracellular VesiclesAnimalsGliomaHumansInterferon-gammaSignal TransductionPhosphatidylinositol 3-KinasesCell Line, TumorPTEN PhosphohydrolaseTumor MicroenvironmentB7-H1 Antigen

Keywords

PTENBiogenesisExtracellular vesiclesExtracellularGliomaPI3K/AKT/mTOR pathwayCell biologyExtracellular vesicleMicrovesiclesChemistryCell cultureCancer researchVesicleBiologySignal transductionBiochemistryGeneticsGenemicroRNAMembraneGlioblastomaimmunosuppressionPhosphatase And Tensin Homolog (Pten)Phosphatidylinositide 3-Kinase (Pi 3-Kinase)PTEN PhosphohydrolaseArticleB7-H1 AntigenPhosphatidylinositol 3-KinasesInterferon-gammaCell Line, TumorTumor MicroenvironmentHumansAnimalsResearch Article

Sustainable Development Goals

SDG 3: 3. Good health