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Phosphodiesterase 5 expression in photoreceptors rescues retinal degeneration induced by deregulation of membrane guanylyl cyclase

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108265Source: DataRank Database

Phosphodiesterase 5 expression in photoreceptors rescues retinal degeneration induced by deregulation of membrane guanylyl cyclase is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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0DataRank · unranked

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 1.19)OA: goldTopics (51)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Shinya Sato ORCID,Zhuokai Luo,Lyuqi Tan,Fay E Levin,Elena V. Olshevskaya

Live enrichment

PubMed:39909376 PMC:PMC11923828 OpenAlex:https://openalex.org/W4407095858

NEI NIH HHS

Grant: R01 EY034861

NEI NIH HHS

Grant: R01 EY011522

NEI NIH HHS

Grant: R01 EY035884

NEI NIH HHS

Grant: R01 EY035137

Pennsylvania Department of Health

National Eye Institute

FWCI

1.19

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(25)00112-7/pdf

publisherhttps://www.jbc.org/article/S0021-9258(25)00112-7/pdf

journalhttps://doi.org/10.1016/j.jbc.2025.108265

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39909376

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11923828

Fields of Study

Retinal Development and DisordersPhosphodiesterase function and regulationRetinal Diseases and TreatmentsAnimalsRetinal DegenerationMiceCyclic Nucleotide Phosphodiesterases, Type 5Guanylate CyclaseCyclic GMPRetinal Rod Photoreceptor CellsMice, TransgenicHumansGuanylate Cyclase-Activating ProteinsReceptors, Cell Surface

MeSH Terms

AnimalsCyclic GMPGuanylate CyclaseHumansMice, TransgenicReceptors, Cell SurfaceRetinal DegenerationRetinal Rod Photoreceptor CellsMiceGuanylate Cyclase-Activating ProteinsCyclic Nucleotide Phosphodiesterases, Type 5

Keywords

PhosphodiesteraseGuanylate cyclaseSoluble guanylyl cyclaseDegeneration (medical)Cell biologyDeregulationChemistryCyclaseGUCY2DMembraneBiochemistryBiologyEnzymeGuanylate cyclase 2CMedicinePathologyCalcium binding proteinsEyeRetinal degenerationphotoreceptorPde5GcapCyclic Gmp (Cgmp)Guanylate Cyclase (Guanylyl Cyclase)RetgcGuca1a