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Mechanistic insights into mutation in the proton-coupled folate transporter (SLC46A1) causing hereditary folate malabsorption

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108280Source: DataRank Database

Mechanistic insights into mutation in the proton-coupled folate transporter (SLC46A1) causing hereditary folate malabsorption is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (7 grants)Impact (FWCI 0.00)OA: goldTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

I. David Goldman,András Fiser ORCID,Prithviraj Nandigrami ORCID

Live enrichment

PubMed:39924111 PMC:PMC11929075 OpenAlex:https://openalex.org/W4407249310

NIAID

Grant: AI141816

NIGMS

Grant: GM136357

NIAID NIH HHS

Grant: R01 AI141816

NIGMS NIH HHS

Grant: R35 GM136357

National Institutes of Health

Grant: 5R35GM136357-02

Molecular basis of recognition in the Immunological Synapse

National Institutes of Health

Grant: 5R01AI141816-06

Interdisciplinary protein engineering approach to design high affinity antibodies for flaviviruses

National Institutes of Health

FWCI

0.00

Citation Percentile

0.0%

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(25)00128-0/pdf

GOLDhttps://doi.org/10.1016/j.jbc.2025.108280

publisherhttps://www.jbc.org/article/S0021-9258(25)00128-0/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925825001280?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825001280?httpAccept=text/plain

Fields of Study

Folate and B Vitamins ResearchRNA regulation and diseasePorphyrin Metabolism and DisordersMedicineBiology0303 health sciences03 medical and health sciencesProton-Coupled Folate TransporterHumansMalabsorption SyndromesMolecular Dynamics SimulationMutationMetabolism, Inborn ErrorsFolic AcidAnimalsGenetic Diseases, InbornFolic Acid DeficiencyFolate Malabsorption, Hereditary

MeSH Terms

AnimalsFolic AcidFolic Acid DeficiencyHumansMalabsorption SyndromesMetabolism, Inborn ErrorsMutationGenetic Diseases, InbornMolecular Dynamics SimulationProton-Coupled Folate Transporter

Keywords

Loss functionMutantMutationBiologyGeneChoroid plexusGeneticsTransporterPhenotypeEndocrinologyCentral nervous systemMolecular Dynamics SimulationsPcftHereditary Folate MalabsorptionSlc46a1Inactivating And Compensatory MutationsFolic AcidMalabsorption SyndromesGenetic Diseases, InbornHumansAnimalsMolecular Dynamics SimulationFolic Acid DeficiencyResearch Article Collection: Computational BiologyProton-Coupled Folate TransporterMetabolism, Inborn Errors

Sustainable Development Goals

SDG 0: Zero hunger