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Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity in cells

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108361Source: DataRank Database

Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity in cells is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0.269. It has been cited 5 times.

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0.269DataRank · unranked

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5 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (19 grants)OA: goldTopics (26)IDs (PubMed, PMC)

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Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.269

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (7)

Seher Alam ORCID,Alen Lovrić ORCID,Emanuele Fabbrizi,Dante Rotili ORCID,Mikael Altun ORCID

Live enrichment

PubMed:40021124 PMC:PMC11986510

Novo Nordisk Foundation

Grant: NNF22OC0076798

Horizon 2020 Marie Skłodowska-Curie Actions

Grant: 859860

Innovative strategies for cancer prevention with focus on sex hormone signaling and chronic inflammation

Ministero dell’Istruzione, dell’Università e della Ricerca

Grant: PNRR-M4C2

Ministero dell’Istruzione, dell’Università e della Ricerca

Grant: CUP B53C22004000006

Ministero dell’Istruzione, dell’Università e della Ricerca

Grant: PE_00000019

Childhood Cancer Foundation

Grant: TJ2019\u20130036

Loo and Hans Osterman Foundation for Medical Research

Grant: 2020-01208

Cancerfonden

Grant: 21 0352 PT \u2013 NV

Cancerfonden

Grant: 21 0352 PT

Karolinska Institute

Grant: unidentified

unidentified

SciLifeLab

Bertil Hållsten's Research Foundation

European Commission

Novo Nordisk

Ministero dell'Università e della Ricerca

Horizon 2020

Karolinska Institutet

Felix Mindus Foundation's contribution to leukemia research

Horizon 2020 Framework Programme

goldLicense: cc-by

publisherhttps://www.jbc.org/article/S0021-9258(25)00210-8/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925825002108?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825002108?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11986510

Europe_PMChttps://europepmc.org/articles/PMC11986510

MeSH Terms

HumansPiperazinesPhthalazinesPoly(ADP-ribose) PolymerasesBiosensing TechniquesPoly(ADP-ribose) Polymerase InhibitorsPoly (ADP-Ribose) Polymerase-1

Keywords

PharmacologyProtein engineeringFluorescenceBiosensordrug discoveryParp InhibitorsDrug SelectivityHpf1Cellular Target EngagementCeteamPoly (ADP-Ribose) Polymerase-1HumansPhthalazinesBiosensing TechniquesCeTEAM; HPF1; PARP inhibitors; biosensor; cellular target engagement; drug discovery; drug selectivity; fluorescence; pharmacology; protein engineeringPoly(ADP-ribose) Polymerase InhibitorsPoly(ADP-ribose) PolymerasesPiperazinesResearch Article

Duplexed CeTEAM drug biosensors reveal determinants of PARP inhibitor selectivity in cells

FAIR Checklist

DataRank Breakdown

Authors (7)

Funding (19 grants)

Open Access

Topics