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Cardioprotective effect of genetic ablation of the G-protein-coupled receptor kinase GRK2 in adult pancreatic β-cells during high-fat diet

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108388Source: DataRank Database

Cardioprotective effect of genetic ablation of the G-protein-coupled receptor kinase GRK2 in adult pancreatic β-cells during high-fat diet is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 2.19)OA: goldTopics (44)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Chunsun Jiang,Ran Hee Choi ORCID,Taylor Morgan,Jeffrey Roman,Lilly Underwood

Live enrichment

PubMed:40054692 PMC:PMC12018985 OpenAlex:https://openalex.org/W4408254132

National Heart Lung and Blood Institute

Grant: R01HL163666

National Heart Lung and Blood Institute

Grant: R56HL149887

NIDDK NIH HHS

Grant: P30 DK079626

NIDDK NIH HHS

Grant: P30 DK019525

National Institutes of Health

Grant: 1R56HL149887-01A1

Non-canonical role of GRK2 in mediating cardiac function

National Institutes of Health

Grant: 5R01HL163666-04

Dysregulation of cardiac signaling in disease and stress

National Institutes of Health

FWCI

2.19

Citation Percentile

0.8%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.jbc.org/action/showPdf?pii=S0021925825002376

publisherhttps://www.jbc.org/action/showPdf?pii=S0021925825002376

publisherhttps://api.elsevier.com/content/article/PII:S0021925825002376?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825002376?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2025.108388

Fields of Study

Pancreatic function and diabetesMetabolism, Diabetes, and CancerDiabetes Treatment and Management0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsMaleMyocardiumObesityMice, KnockoutInsulin-Secreting CellsMiceG-Protein-Coupled Receptor Kinase 2Diet, High-Fat

Keywords

Beta adrenergic receptor kinaseEndocrinologyInternal medicinePancreatic isletsCardiac function curveCardiac dysfunctionDiabetes mellitusReceptorMedicineBiologyIsletKnockout mouseType 2 diabetesHeart failureG protein-coupled receptorInsulinHeartGlucoseObesityDiabetesGrk2Mice, KnockoutMaleMiceG-Protein-Coupled Receptor Kinase 2Insulin-Secreting CellsMyocardiumAnimalsDiet, High-FatResearch Article

Sustainable Development Goals

SDG 0: Good health and well-being