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In vitro inhibition of voltage-dependent sodium currents by the antifungal drug amorolfine

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108407Source: DataRank Database

In vitro inhibition of voltage-dependent sodium currents by the antifungal drug amorolfine is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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Enrichment:Funding (7 grants)Impact (FWCI 0.25)OA: goldTopics (37)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Sidharth Tyagi ORCID,Philip R. Effraim ORCID,Stephen G. Waxman ORCID,Mohammad‐Reza Ghovanloo ORCID

Live enrichment

PubMed:40090585 PMC:PMC12004706 OpenAlex:https://openalex.org/W4408422589

Canadian Institutes of Health Research

Grant: 471896

National Institute of Neurological Disorders and Stroke

Grant: 1F31NS135909-01

National Institute of Neurological Disorders and Stroke

Grant: T32GM136651

NINDS NIH HHS

Grant: F31 NS135909

National Institutes of Health

Rehabilitation Research and Development Service

Yale University

FWCI

0.25

Citation Percentile

0.3%

Citation Trend

2025

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(25)00256-X/pdf

publisherhttps://www.jbc.org/article/S0021-9258(25)00256-X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S002192582500256X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S002192582500256X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2025.108407

Fields of Study

Electrochemical Analysis and ApplicationsIon channel regulation and functionCholinesterase and Neurodegenerative DiseasesHumansAntifungal AgentsVoltage-Gated Sodium Channel BlockersAnimalsMorpholinesVoltage-Gated Sodium ChannelsHEK293 CellsXenopus laevis

MeSH Terms

AnimalsAntifungal AgentsHumansMorpholinesXenopus laevisHEK293 CellsVoltage-Gated Sodium ChannelsVoltage-Gated Sodium Channel Blockers

Keywords

In vitroAntifungalDrugChemistryPharmacologyAntifungal drugsAntifungal drugBiologyBiochemistryMicrobiologyPatch-clampPhysicochemical propertiesVoltage Clampvoltage-gated sodium channelNav1.7AmorolfineModulated Receptor HypothesisUltra-hydrophobic Pathway

In vitro inhibition of voltage-dependent sodium currents by the antifungal drug amorolfine

FAIR Checklist

Authors (4)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)