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Kinetic mechanism of ENPP1 ATPase: Implications for aberrant calcification disorders and enzyme replacement therapy

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110558Source: DataRank Database

Kinetic mechanism of ENPP1 ATPase: Implications for aberrant calcification disorders and enzyme replacement therapy is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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0DataRank · unranked

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 3.69)OA: goldTopics (39)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Tony Potchernikov,Ethan R. Lester ORCID,Demetrios T. Braddock ORCID,Wenxiang Cao ORCID,Enrique M. De La Cruz ORCID

Live enrichment

PubMed:40769408 PMC:PMC12446537 OpenAlex:https://openalex.org/W4412988199

NIH National Institute of General Medical Sciences

Grant: R35 GM136656

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Grant: R01AR080416

Inozyme Pharma

National Institutes of Health

Yale College

FWCI

3.69

Citation Percentile

0.9%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(25)02409-3/pdf

publisherhttps://www.jbc.org/article/S0021-9258(25)02409-3/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925825024093?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825024093?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2025.110558

Fields of Study

Dermatological and Skeletal DisordersParathyroid Disorders and TreatmentsHeterotopic Ossification and Related ConditionsPhosphoric Diester HydrolasesPyrophosphatasesHumansKineticsEnzyme Replacement TherapyAdenosine TriphosphateHydrolysisDiphosphatesVascular CalcificationAdenosine Monophosphate

MeSH Terms

Adenosine MonophosphateAdenosine TriphosphateHumansHydrolysisKineticsPhosphoric Diester HydrolasesPyrophosphatasesDiphosphatesEnzyme Replacement TherapyVascular Calcification

Keywords

ATPaseMechanism (biology)EnzymeCalcificationChemistryEnzyme replacement therapyBiochemistryMedicineInternal medicinePhilosophyDiseaseKineticsBiomineralizationEnzymologyEnpp1Gaci

Sustainable Development Goals

SDG 0: Zero hunger