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From pores to rupture: Structural basis and regulation of lytic cell death by gasdermins and NINJ1

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110698Source: DataRank Database

From pores to rupture: Structural basis and regulation of lytic cell death by gasdermins and NINJ1 is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0. It has been cited 11 times.

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Open Access11 citations

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Enrichment:Funding (2 grants)Impact (FWCI 4.37)OA: goldTopics (36)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

BE Dreyer,Evelyn Teran,Jianbin Ruan ORCID,Chengliang Wang ORCID

Live enrichment

PubMed:40946739 PMC:PMC12547243 OpenAlex:https://openalex.org/W4414167973

National Institute of Allergy and Infectious Diseases Division of Intramural Research

Grant: R01AI158435

National Institutes of Health

FWCI

4.37

Citation Percentile

1.0%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(25)02550-5/pdf

publisherhttps://www.jbc.org/article/S0021-9258(25)02550-5/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925825025505?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825025505?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2025.110698

Fields of Study

Toxin Mechanisms and ImmunotoxinsEndoplasmic Reticulum Stress and DiseaseSkin and Cellular Biology ResearchHumansCell Adhesion Molecules, NeuronalAnimalsCell MembranePyroptosisCell DeathProtein Processing, Post-TranslationalNeoplasm ProteinsGasderminsPhosphate-Binding Proteins

MeSH Terms

PyroptosisGasderminsAnimalsCell MembraneHumansNeoplasm ProteinsProtein Processing, Post-TranslationalCell Adhesion Molecules, NeuronalCell DeathPhosphate-Binding Proteins

Keywords

Lytic cycleProgrammed cell deathEffectorCellCytoskeletonMechanism (biology)necrosisPyroptosisNinj1Ninjurin 1Membrane RuptureGasderminGsdm

From pores to rupture: Structural basis and regulation of lytic cell death by gasdermins and NINJ1

FAIR Checklist

Authors (4)

Funding (2 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)